Trial reportNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2015
Opposing effects of oxytocin on overt compliance and lasting changes to memory.
Trial report in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Role of Oxytocin in Antisocial Personality Disorders: A Systematic Review of the Literature.Frontiers in psychiatry · 2019Pooled it
- Oxytocin-enforced norm compliance reduces xenophobic outgroup rejection.Proceedings of the National Academy of Sciences of the United States of America · 2017Trial
- Oxytocin conditions trait-based rule adherence.Social cognitive and affective neuroscience · 2017Trial
- Oxytocin in autism: Rethinking treatment and research through a neurodivergent perspective.Psychoneuroendocrinology · 2025Article
- The Role of Oxytocin and Vasopressin in People with Borderline Personality Disorder: A Closer Look at Adolescents.International journal of molecular sciences · 2024Review
- Enhanced endogenous oxytocin signaling in the brain modulates neural responses to social misalignment and promotes conformity in humans: A multi-locus genetic profile approach.Psychoneuroendocrinology · 2022Article
- Oxytocin has 'tend-and-defend' functionality in group conflict across social vertebrates.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Infection threat shapes our social instincts.Behavioral ecology and sociobiology · 2021Review
- Salivary Oxytocin Is Negatively Associated With Religious Faith in Japanese Non-Abrahamic People.Frontiers in psychology · 2021Article
- Social Conformity in Autism.Journal of autism and developmental disorders · 2019Article
- Oxytocin Facilitates Social Learning by Promoting Conformity to Trusted Individuals.Frontiers in neuroscience · 2019Review
- Perspective: Neuroregenerative Nutrition.Advances in nutrition (Bethesda, Md.) · 2017Article
- The Neuropeptide Oxytocin Enhances Information Sharing and Group Decision Making Quality.Scientific reports · 2017Article
- How beliefs about self-creation inflate value in the human brain.Frontiers in human neuroscience · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
From infancy we learn to comply with societal norms. However, overt compliance is not necessarily accompanied by a change in internal beliefs. The neuromodulatory processes underlying these different phenomena are not yet understood. Here, we test the role of oxytocin in controlling overt compliance versus internalization of information delivered by a social source. After intranasal oxytocin administration, participants showed enhanced compliance to the erroneous opinion of others. However, this expression was coupled with a decrease in the influence of others on long-term memories. Our data suggest that this dissociation may result from reduced conflict in the face of social pressure, which increases immediate conforming behavior, but reduces processing required for deep encoding. These findings reveal a neurobiological control system that oppositely affects internalization and overt compliance.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.