ReviewHandbook of clinical neurology2014
Alcohol and the sleeping brain.
Review in Handbook of clinical neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
93 citing papers in PubMed, 1 synthesis or guideline pooled it, 192 citations in OpenAlex.
- The Impact of Physical Activity on Sleep in Alcohol Users: A Systematic Review.Addiction biology · 2025Pooled it
- Lactiplantibacillus plantarum Lp815 improves sleep and increases urinary GABA in a randomized, double-blind, placebo-controlled study of sleep disturbance.Scientific reports · 2026Trial
- Influence of sleep quality on lapse to alcohol use during a quit attempt.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024Trial
- Insomnia and Its Therapeutic Approaches Among University Students in Madrid.Current therapeutic research, clinical and experimental · 2026Article
- Review
- Development and validation of a nomogram for prediction postoperative sleep disorders in patients with oral cancer: a prospective study.Frontiers in oncology · 2026Article
- Lifestyle Mediates the Associations of Social Media and Smartphone Use Addiction with Sleep Quality and Mental Health Problems in Adults: An Exploratory Study.Psychology research and behavior management · 2026Article
- Cannabis and Alcohol Use to Initiate Sleep Among Young Adults.JAMA pediatrics · 2025Article
- The Beauty Sleep to Keep a Healthy Liver.International journal of molecular sciences · 2025Review
- Deep sleep homeostatic response to naturalistic sleep loss.PLOS digital health · 2025Article
- Alcohol Use Predicts Longer But More Fragmented Sleep: A Daily Diary Study of Alcohol, Sleep, and PTSD in Nurses.International journal of behavioral medicine · 2025Article
- Prevalence, risk factors, and metabolic implications of alcohol use disorders among male workers in Hebei Province, China: a cross-sectional study.Substance abuse treatment, prevention, and policy · 2025Article
- Sleep quality in older adults with cognitive frailty: current status and influencing factors.BMC geriatrics · 2025Article
- Nutritional and Lifestyle Behaviors and Their Influence on Sleep Quality Among Spanish Adult Women.Nutrients · 2025Article
- Glycemic Variability and Control by CGM in Healthy Older and Young Adults and Their Relationship With Diet.Journal of the Endocrine Society · 2025Article
- Unraveling the nutritional challenges in epilepsy: Risks, deficiencies, and management strategies: A systematic review.World journal of experimental medicine · 2025Article
- Threshold Values of Sleep Spindles Features in Healthy Adults Using Scalp-EEG and Associations With Sleep Parameters.Annals of clinical and translational neurology · 2025Observational
- Sleep quality trajectories and their relationship with quality of life in patients with hepatocellular carcinoma: a prospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Alcohol induces long-lasting sleep deficits in Drosophila via subsets of cholinergic neurons.Current biology : CB · 2025Article
- Poor sleep quality and its determinants among stroke survivors in Northwest Ethiopia.Scientific reports · 2025Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
Abstract
Alcohol acts as a sedative that interacts with several neurotransmitter systems important in the regulation of sleep. Acute administration of large amounts of alcohol prior to sleep leads to decreased sleep-onset latency and changes in sleep architecture early in the night, when blood alcohol levels are high, with subsequent disrupted, poor-quality sleep later in the night. Alcohol abuse and dependence are associated with chronic sleep disturbance, lower slow-wave sleep, and more rapid-eye-movement sleep than normal, that last long into periods of abstinence and may play a role in relapse. This chapter outlines the evidence for acute and chronic alcohol effects on sleep architecture and sleep electroencephalogram, evidence for tolerance with repeated administration, and possible underlying neurochemical mechanisms for alcohol's effects on sleep. Also discussed are sex differences as well as effects of alcohol on sleep homeostasis and circadian regulation. Evidence for the role of sleep disruption as a risk factor for developing alcohol dependence is discussed in the context of research conducted in adolescents. The utility of sleep-evoked potentials in the assessment of the effects of alcoholism on sleep and the brain and in abstinence-mediated recovery is also outlined. The chapter concludes with a series of questions that need to be answered to determine the role of sleep and sleep disturbance in the development and maintenance of problem drinking and the potential beneficial effects of the treatment of sleep disorders for maintenance of abstinence in alcoholism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.