Evidence map›Paper›PMID 25307587›Full record

ReviewHandbook of clinical neurology2014

Understanding alcohol use disorders with neuroelectrophysiology.

Madhavi Rangaswamy, Bernice Porjesz

Abstract readReview
In one paragraph

Review in Handbook of clinical neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Madhavi RangaswamyHenri Begleiter Neurodynamics Laboratory, Department of Psychiatry and Behavioral Sciences, SUNY Downstate Medical Center, Brooklyn, NY, USA.
Bernice PorjeszHenri Begleiter Neurodynamics Laboratory, Department of Psychiatry and Behavioral Sciences, SUNY Downstate Medical Center, Brooklyn, NY, USA. Electronic address: bp@hbnl.downstate.edu.

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI JESSICA E SALVATORE · 1989 to 2026
$162.7M
BRAIN DYSFUNCTION AND ALCOHOLISMR01AA002686 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI PORJESZ, BERNICE · 1985 to 2018
$9.6M
NEUROPHYSIOLOGY IN CHILDREN AT HIGH RISK FOR ALCOHOLISMR01AA005524 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI PORJESZ, BERNICE · 1986 to 2015
$3.0M
NIAAA NIH HHS R01 AA002686NIAAA NIH HHS R01AA002686NIAAA NIH HHS R01 AA005524NIAAA NIH HHS R01AA005524NIAAA NIH HHS U10AA008401
6 · The paper itself

Abstract

Neurocognitive deficits associated with impairments in various brain regions and neural circuitries, particularly involving frontal lobes, have been associated with chronic alcoholism, as well as with a predisposition to develop alcohol use and related disorders (AUDs). AUD is a multifactorial disorder caused by complex interactions between behavioral, genetic, and environmental liabilities. Neuroelectrophysiologic techniques are instrumental in understanding brain and behavior relationships and have also proved very useful in evaluating the genetic diathesis of alcoholism. This chapter describes findings from neuroelectrophysiologic measures (electroencephalogram, event-related potentials, and event-related oscillations) related to acute and chronic effects of alcohol on the brain and those that reflect underlying deficits related to a predisposition to develop AUDs and related disorders. The utility of these measures as effective endophenotypes to identify and understand genes associated with brain electrophysiology, cognitive networks, and AUDs has also been discussed.

Indexed as

ComprehensionAlcohol DrinkingAlcohol-Related DisordersAnimalsBrainElectroencephalographyEvoked PotentialsFrontal LobeHumansalcoholismcognitionEEGERPoscillations

Identifiers

PMID25307587
PMCPMC4331067

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.