ReviewHandbook of clinical neurology2014
Profiles of impaired, spared, and recovered neuropsychologic processes in alcoholism.
Review in Handbook of clinical neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
92 citing papers in PubMed, 5 syntheses or guidelines pooled it, 164 citations in OpenAlex.
- Executive Function in Gambling Disorder: A Meta-analysis on Neuropsychological Evidence.Journal of gambling studies · 2025Pooled it
- Meta-analysis of associations between empathy and alcohol use and problems in clinical and non-clinical samples.Addiction (Abingdon, England) · 2022Pooled it
- Systematic review and meta-analysis on the association between theory of mind and alcohol problems in non-clinical samples.Alcoholism, clinical and experimental research · 2022Pooled it
- Meta-analysis of grey matter changes and their behavioral characterization in patients with alcohol use disorder.Scientific reports · 2021Pooled it
- Eye Tracking Studies Exploring Cognitive and Affective Processes among Alcohol Drinkers: a Systematic Review and Perspectives.Neuropsychology review · 2021Pooled it
- The impact of empathy on drinking motives, craving, and drink orders: An experimental study.Alcohol, clinical & experimental research · 2025Trial
- Cognitive training in recently-abstinent individuals with alcohol use disorder improves emotional stroop performance: Evidence from a randomized pilot trial.Drug and alcohol dependence · 2022Trial
- Virtual Reality Cognitive Training Among Individuals With Alcohol Use Disorder Undergoing Residential Treatment: Pilot Randomized Controlled Trial.Journal of medical Internet research · 2021Trial
- Using deep learning to identify brain networks mediating cognitive and motor impairments in alcohol use disorder.Translational psychiatry · 2026Article
- Validity and reliability of a cognitive function assessment tool using psychomotor function tests in patients with alcohol use disorders - a pilot study.Journal of pharmaceutical health care and sciences · 2026Article
- Alcohol Cues Elicit Differences in Brain Activation Patterns of Abstinent Men and Women with Alcohol Use Disorders.Neuropsychiatric disease and treatment · 2026Article
- Neural correlates of altered loss aversion in alcohol use disorder: preliminary evidence of sex-related differences from 18F-FDG-PET imaging.Frontiers in psychiatry · 2026Article
- Neuroanatomical features reveal accelerated brain age in alcohol use disorder.bioRxiv : the preprint server for biology · 2025Article
- A narrative review on alcohol use in women: insight into the telescoping hypothesis from a biopsychosocial perspective.The American journal of drug and alcohol abuse · 2025Review
- Cognitive and cerebral phenotypes of neurocognitive disorders due to alcohol or Alzheimer's disease.Brain communications · 2025Article
- No relation between Body Mass Index and neurocognitive recovery in abstinent alcohol dependent patients?PloS one · 2025Article
- Spontaneous flexibility, attentional set shifting and cognitive control in men with alcohol dependence.Postepy psychiatrii neurologii · 2024Article
- Cognitive Alterations Associated with Remission and Alcohol Dependence Severity in Ethnically Diverse Patients of Siberia.Clinical practice and epidemiology in mental health : CP & EMH · 2024Article
- Fine-Grained Intoxicated Gait Classification Using a Bilinear CNN.IEEE sensors journal · 2023Article
- Anterior cingulate metabolite levels, memory, and inhibitory control in abstinent men and women with alcohol use disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2023Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Long-term chronic alcoholism is associated with disparate and widespread residual consequences for brain functioning and behavior, and alcoholics suffer a variety of cognitive deficiencies and emotional abnormalities. Alcoholism has heterogeneous origins and outcomes, depending upon factors such as family history, age, gender, and mental or physical health. Consequently, the neuropsychologic profiles associated with alcoholism are not uniform among individuals. Moreover, within and across research studies, variability among subjects is substantial and contributes to characteristics associated with differential treatment outcomes after detoxification. In order to refine our understanding of alcoholism-related impaired, spared, and recovered abilities, we focus on five specific functional domains: (1) memory; (2) executive functions; (3) emotion and psychosocial skills; (4) visuospatial cognition; and (5) psychomotor abilities. Although the entire brain might be vulnerable in uncomplicated alcoholism, the brain systems that are considered to be most at risk are the frontocerebellar and mesocorticolimbic circuitries. Over time, with abstinence from alcohol, the brain appears to become reorganized to provide compensation for structural and behavioral deficits. By relying on a combination of clinical and scientific approaches, future research will help to refine the compensatory roles of healthy brain systems, the degree to which abstinence and treatment facilitate the reversal of brain atrophy and dysfunction, and the importance of individual differences to outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.