Evidence map›Paper›PMID 25304986›Full record

Trial reportJournal of cancer survivorship : research and practice2015

Objectively measured physical activity and cognitive functioning in breast cancer survivors.

Catherine R Marinac, Suneeta Godbole, Jacqueline Kerr, Loki Natarajan, Ruth E Patterson, Sheri J Hartman

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cancer survivorship : research and practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Effects of Baduanjin exercise on cognitive function and cancer-related symptoms in women with breast cancer receiving chemotherapy: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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  17. Physical activity, cardiorespiratory fitness, and cognitive function in postmenopausal women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Catherine R MarinacMoores UCSD Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Suneeta Godbole
Jacqueline Kerr
Loki Natarajan
Ruth E Patterson
Sheri J Hartman
University of California, San Diego · US

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DIANE M SIMEONE · 1985 to 2026
$124.9M
UCSD Biorepository Shared ResourceU54CA155435 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KERR, JACQUELINE · 2011 to 2015
$9.1M
Physical Activity and neuropsychological outcomes in a cancer populationK07CA181323 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HARTMAN, SHERI J · 2014 to 2018
$852k
Transdisciplinary Training for Predoctoral Behavioral ScientistsT32GM084896 · NIGMS · SAN DIEGO STATE UNIVERSITY · PI HOVELL, MELBOURNE F · 2008 to 2012
$789k
NCI NIH HHS K07 CA181323NCI NIH HHS U54 CA155435NCI NIH HHS U54 CA155435-01NIGMS NIH HHS 5 T32GM084896NIGMS NIH HHS T32 GM084896
6 · The paper itself

Abstract

purposeThis study aimed to explore the relationship between objectively measured physical activity and cognitive functioning in breast cancer survivors.

methodsParticipants were 136 postmenopausal breast cancer survivors. Cognitive functioning was assessed using a comprehensive computerized neuropsychological test. Seven-day physical activity was assessed using hip-worn accelerometers. Linear regression models examined associations of minutes per day of physical activity at various intensities on individual cognitive functioning domains. The partially adjusted model controlled for primary confounders (model 1), and subsequent adjustments were made for chemotherapy history (model 2) and body mass index (BMI) (model 3). Interaction and stratified models examined BMI as an effect modifier.

resultsModerate-to-vigorous physical activity (MVPA) was associated with information processing speed. Specifically, 10 min of MVPA was associated with a 1.35-point higher score (out of 100) on the information processing speed domain in the partially adjusted model and a 1.29-point higher score when chemotherapy was added to the model (both p < 0.05). There was a significant BMI × MVPA interaction (p = 0.051). In models stratified by BMI (<25 vs. ≥25 kg/m(2)), the favorable association between MVPA and information processing speed was stronger in the subsample of overweight and obese women (p < 0.05) but not statistically significant in the leaner subsample. Light-intensity physical activity was not significantly associated with any of the measured domains of cognitive function.

conclusionsMVPA may have favorable effects on information processing speed in breast cancer survivors, particularly among overweight or obese women. IMPLICATIONS FOR CANCER SURVIVORS: Interventions targeting increased physical activity may enhance aspects of cognitive function among breast cancer survivors.

Indexed as

SurvivorsAgedBody Mass IndexBreast NeoplasmsCognitionExerciseFemaleHumansMiddle AgedMotor ActivityNeuropsychological TestsObesityOverweight

Identifiers

PMID25304986
PMCPMC4393781
OpenAlexW1973200804

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.