Evidence map›Paper›PMID 25304961›Full record

ReviewCurrent opinion in pediatrics2014

Pediatric status epilepticus management.

Nicholas S Abend, Tobias Loddenkemper

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Current opinion in pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04829838 (Comparison of Efficacy of Phenytoin With Levetireacetam for the Management of Children With Status Epilepticus), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04829838 phase4unknown statusnot on this mapstarted 2019, after this paper: background citation

Comparison of Efficacy of Phenytoin With Levetireacetam for the Management of Children With Status Epilepticus

TypeinterventionalSponsorayesha tariqRan2019 to 2021Enrolled244ConditionsStatus EpilepticusArmsintravenous levetireacetam
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Observational
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. [Paediatric status epilepticus].Revista de neurologia · 2022
    Review
  13. Article
  14. Article
  15. Anticonvulsant and Neuroprotective Effects of Dexmedetomidine on Pilocarpine-Induced Status Epilepticus in Rats Using a Metabolomics Approach.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  16. Article
  17. Observational
  18. Article
  19. Pediatric Boot Camp Series: Infant With Altered Mental Status and Seizure-A Case of Child Abuse.MedEdPORTAL : the journal of teaching and learning resources · 2017
    Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicholas S AbendaDepartments of Neurology and Pediatrics, The Children's Hospital of Philadelphia bPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania cDivision of Epilepsy and Clinical Neurophysiology, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Tobias Loddenkemper
Harvard University · US

Funding

Non-convulsive seizures in critically ill children:physiology and outcomeK23NS076550 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI ABEND, NICHOLAS SCOTT · 2011 to 2015
$877k
NINDS NIH HHS K23 NS076550NINDS NIH HHS K23NS076550
6 · The paper itself

Abstract

purpose of reviewThis review discusses the management of status epilepticus in children, including both anticonvulsant medications and overall management approaches. RECENT

findingsRapid management of status epilepticus is associated with a greater likelihood of seizure termination and better outcomes, yet data indicate that there are often management delays. This review discusses an overall management approach aiming to simultaneously identify and manage underlying precipitant causes, administer anticonvulsants in rapid succession until seizures have terminated, and identify and manage systemic complications. An example management pathway is provided. SUMMARY: Status epilepticus is a common neurologic emergency in children and requires rapid intervention. Having a predetermined status epilepticus management pathway can expedite management.

Indexed as

Airway ManagementAnticonvulsantsChildDisease ManagementFluid TherapyHumansPractice Guidelines as TopicStatus EpilepticusVital SignsAnticonvulsants

Identifiers

PMID25304961
PMCPMC4277681
OpenAlexW2023617220

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.