ArticlePsychopharmacology2015
Nicotine reduces distraction under low perceptual load.
Article in Psychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Increased dopamine availability magnifies nicotine effects on cognitive control: A pilot study.Journal of psychopharmacology (Oxford, England) · 2020Trial
- Nicotine enhances auditory processing in healthy and normal-hearing young adult nonsmokers.Psychopharmacology · 2020Trial
- Effects of nicotine on smooth pursuit eye movements in healthy non-smokers.Psychopharmacology · 2019Trial
- Moderation of nicotine effects on covert orienting of attention tasks by poor placebo performance and cue validity.Pharmacology, biochemistry, and behavior · 2016Trial
- Effects of initial nicotine exposure on cognition and nicotine reinforcement among non-smoking young adults with and without attention deficit hyperactivity disorder.Journal of psychopharmacology (Oxford, England) · 2025Article
- Nicotine Enhances Amplitude and Consistency of Timing of Responses to Acoustic Trains in A1.Frontiers in neural circuits · 2021Article
- Cognitive performance effects of nicotine and industry affiliation: a systematic review.Substance abuse : research and treatment · 2020Article
- Modulation of nicotine effects on selective attention by DRD2 and CHRNA4 gene polymorphisms.Psychopharmacology · 2015Article
- Nicotinergic Modulation of Attention-Related Neural Activity Differentiates Polymorphisms of DRD2 and CHRNA4 Receptor Genes.PloS one · 2015Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleSeveral studies provide evidence that nicotine alleviates the detrimental effects of distracting sensory stimuli. It is been suggested that nicotine may either act as a stimulus filter that prevents irrelevant stimuli entering awareness or by enhancing the attentional focus to relevant stimuli via a boost in processing capacity.
objectivesTo differentiate between these two accounts, we administered nicotine to healthy non-smokers and investigated distractor interference in a visual search task with low and high perceptual load to tax processing capacity.
methodsThirty healthy non-smokers received either 7 mg transdermal nicotine or a matched placebo in a double blind within subject design 1 h prior to performing the visual search task with different fixation distractors.
resultsNicotine reduced interference of incongruent distractors, but only under low-load conditions, where distractor effects were large. No effects of nicotine were observed under high-load conditions. Highly distractible subjects showed the largest effects of nicotine.
conclusionsThe findings suggest that nicotine acts primarily as a stimulus filter that prevents irrelevant stimuli from entering awareness in situations of high distractor interference.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.