Evidence map›Paper›PMID 25304853›Full record

ArticleJournal of the American Heart Association2014

Trends in early aspirin use among patients with acute myocardial infarction in China, 2001-2011: the China PEACE-Retrospective AMI study.

Yan Gao, Frederick A Masoudi, Shuang Hu, Jing Li, Haibo Zhang, Xi Li, Nihar R Desai, Harlan M Krumholz, Lixin Jiang, China PEACE Collaborative Group

Registry-linked trialOpen access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01624883 (The China PEACE), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01624883 completednot on this map

The China PEACE (Patient-centered Evaluative Assessment of Cardiac Events Retrospective Study of Acute Myocardial Infarction

TypeobservationalSponsorChina National Center for Cardiovascular DiseasesRan2012 to 2013Enrolled18,000ConditionsCoronary Heart Disease
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Yan GaoNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Y.G., S.H., J.L., H.Z., X.L., L.J.).
Frederick A MasoudiDivision of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO (F.A.M.).
Shuang HuNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Y.G., S.H., J.L., H.Z., X.L., L.J.).
Jing LiNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Y.G., S.H., J.L., H.Z., X.L., L.J.).
Haibo ZhangNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Y.G., S.H., J.L., H.Z., X.L., L.J.).
Xi LiNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Y.G., S.H., J.L., H.Z., X.L., L.J.).
Nihar R DesaiCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT (N.R.D., H.M.K.).
Harlan M KrumholzCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT (N.R.D., H.M.K.).
Lixin JiangNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Y.G., S.H., J.L., H.Z., X.L., L.J.).
China PEACE Collaborative Group
Chinese Academy of Medical Sciences & Peking Union Medical College · CNYale New Haven Hospital · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Center for Cardiovascular Outcomes Research at Yale UniversityU01HL105270 · NHLBI · YALE UNIVERSITY · PI CURTIS, JEPTHA PELHAM, KRUMHOLZ, HARLAN MARC · 2010 to 2013
$5.8M
NHLBI NIH HHS U01 HL105270NHLBI NIH HHS U01 HL105270-03
6 · The paper itself

Abstract

backgroundAspirin is an effective, safe, and inexpensive early treatment of acute myocardial infarction (AMI) with few barriers to administration, even in countries with limited healthcare resources. However, the rates and recent trends of aspirin use for the early treatment of AMI in China are unknown. METHODS AND

resultsUsing data from the China Patient-centered Evaluative Assessment of Cardiac Events Retrospective Study of Acute Myocardial Infarction (China PEACE-Retrospective AMI Study), we identified a cohort of 14 041 patients with AMI eligible for early aspirin therapy. Early use of aspirin for AMI increased over time (78.4% in 2001, 86.5% in 2006, and 90.0% in 2011). However, about 15% of hospitals had a rate of use of <80% in 2011. Treatment was less likely in patients who were older, presented with cardiogenic shock at admission, presented without chest discomfort, had a final diagnosis of non-ST-segment elevation acute myocardial infarction, or did not receive reperfusion therapy. Hospitalization in rural regions was also associated with aspirin underuse.

conclusionsDespite improvements in early use of aspirin for AMI in China, there remains marked variation in practice and opportunities for improvement that are concentrated in some hospitals and patient groups. CLINICAL TRIAL REGISTRATION URL: ClinicalTrials.gov Unique identifier: NCT01624883.

Indexed as

AdultAgedAge FactorsAspirinChinaCohort StudiesConfidence IntervalsDose-Response Relationship, DrugDrug Administration ScheduleFemaleHospital MortalityHumansMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionAspirinacute myocardial infarctionaspirinquality of care

Identifiers

PMID25304853
PMCPMC4323779
OpenAlexW2131265627

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.