ArticleThe Plant cell2014
Arabidopsis TTG2 regulates TRY expression through enhancement of activator complex-triggered activation.
Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 84 citations in OpenAlex.
- Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress.Plant, cell & environment · 2026Review
- Functional Characterisation of HAIRPLUS (NtHAP) Genes Involved in Trichome Development and Specialised Metabolism of Tobacco.Plant biotechnology journal · 2026Article
- Epistatic interaction of the genesbioRxiv : the preprint server for biology · 2026Article
- Exploring the developmental mechanisms of tea plant trichomes using genomics and single-cell transcriptome sequencing.Horticulture research · 2026Article
- Single-cell transcriptomics reveals cellular and genetic mechanisms of alpine adaptation inFrontiers in plant science · 2026Article
- Diversity and ecological functions of anthocyanins.BMC plant biology · 2025Review
- Cellular patterns in Arabidopsis root epidermis emerge from gene regulatory network and diffusion dynamical feedback.NPJ systems biology and applications · 2025Article
- Gibberellin signaling regulates pectin biosynthesis in Arabidopsis.Nature communications · 2025Article
- RsWRKY44 participated in anthocyanin biosynthesis regulation in radish through interaction with RsMYB1a.Plant cell reports · 2025Article
- Genome-wide characterization ofFrontiers in plant science · 2025Article
- The bHLH transcription factor gene EGL3 accounts for the natural diversity in Arabidopsis fruit trichome pattern and morphology.Plant physiology · 2024Article
- A Functional InDel in the WRKY10 Promoter Controls the Degree of Flesh Red Pigmentation in Apple.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Genetic interaction between TTG2 and AtPLC1 reveals a role for phosphoinositide signaling in a co-regulated suite of Arabidopsis epidermal pathways.Scientific reports · 2024Article
- Genome-wide investigation of WRKY gene family inFrontiers in plant science · 2024Article
- MYB-bHLH-TTG1 in a Multi-tiered Pathway Regulates Arabidopsis Seed Coat Mucilage Biosynthesis Genes Including PECTIN METHYLESTERASE INHIBITOR14 Required for Homogalacturonan Demethylesterification.Plant & cell physiology · 2023Article
- Identification of candidate genes associated with less-photosensitive anthocyanin phenotype using an EMS mutant (Frontiers in plant science · 2023Article
- Unraveling the Biosynthesis of Carvacrol in Different Tissues ofInternational journal of molecular sciences · 2022Article
- Differential environmental and genomic architectures shape the natural diversity for trichome patterning and morphology in different Arabidopsis organs.Plant, cell & environment · 2022Article
- ARF2 positively regulates flavonols and proanthocyanidins biosynthesis in Arabidopsis thaliana.Planta · 2022Article
- Developmental regulation of lupulin gland-associated genes in aromatic and bitter hops (Humulus lupulus L.).BMC plant biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trichome patterning in Arabidopsis thaliana is regulated by a regulatory feedback loop of the trichome promoting factors TRANSPARENT TESTA GLABRA1 (TTG1), GLABRA3 (GL3)/ENHANCER OF GL3 (EGL3), and GL1 and a group of homologous R3MYB proteins that act as their inhibitors. Together, they regulate the temporal and spatial expression of GL2 and TTG2, which are considered to control trichome cell differentiation. In this work, we show that TTG2 is a specific activator of TRY (but not CPC or GL2). The WRKY protein TTG2 binds to W-boxes in a minimal promoter fragment of TRY, and these W-boxes are essential for rescue of the try mutant phenotype. We further show that TTG2 alone is not able to activate TRY expression, but rather drastically enhances the activation by TTG1 and GL3. As TTG2 physically interacts with TTG1 and because TTG2 can associate with GL3 through its interaction with TTG1, we propose that TTG2 enhances the activity of TTG1 and GL3 by forming a protein complex.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.