Evidence map›Paper›PMID 25304192›Full record

ReviewPhysiology & behavior2015

Alcohol sensory processing and its relevance for ingestion.

Susan M Brasser, Norma Castro, Brian Feretic

Open access · greenAbstract readReview
In one paragraph

Review in Physiology & behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Influences of ethanol and temperature on sucrose-evoked response of gustatory neurons in the hamster solitary nucleus.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Susan M BrasserDepartment of Psychology, College of Sciences, San Diego State University, San Diego, CA 92120, USA. Electronic address: sbrasser@mail.sdsu.edu.
Norma CastroDepartment of Psychology, College of Sciences, San Diego State University, San Diego, CA 92120, USA.
Brian FereticDepartment of Psychology, College of Sciences, San Diego State University, San Diego, CA 92120, USA.
San Diego State University · US

Funding

Rodents with Genetic Differences in Alcohol PreferenceR24AA015512 · NIAAA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI BELL, RICHARD LOWELL · 2005 to 2014
$5.1M
SENSORY CODING IN TASTER01DC000353 · NIDCD · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI BOUGHTER, JOHN D · 1989 to 2014
$4.5M
Rodents with Genetic Differences in Alcohol PreferenceU24AA015512 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI BELL, RICHARD LOWELL · 2015 to 2019
$2.7M
Orosensory Contributions to Alcohol IngestionR01AA015741 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI BRASSER, SUSAN M · 2007 to 2010
$1.1M
Insular Cortical Processing in Alcohol AddictionR21AA023291 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI BRASSER, SUSAN M · 2014 to 2015
$388k
Gustatory neural coding in mice: connecting taste receptors to the brainR03DC008194 · NIDCD · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI LEMON, CHRISTIAN H · 2006 to 2008
$212k
Effect of amiloride and gurmarin on taste receptor cellsF32DC005270 · NIDCD · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI LEMON, CHRISTIAN H · 2002 to 2003
$85k
MINORITY PREDOCTORAL FELLOWSHIP PROGRAMF31DC000353 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DEWULF, VALERIE D · 1998 to 1999
–
NIAAA NIH HHS AA015512NIAAA NIH HHS AA015741NIAAA NIH HHS AA023291NIAAA NIH HHS R01 AA015741NIAAA NIH HHS R21 AA023291NIAAA NIH HHS R24 AA015512NIAAA NIH HHS U24 AA015512NIDCD NIH HHS DC00353NIDCD NIH HHS DC005270NIDCD NIH HHS DC008194NIDCD NIH HHS F31 DC000353NIDCD NIH HHS F32 DC005270NIDCD NIH HHS R01 DC000353NIDCD NIH HHS R03 DC008194
6 · The paper itself

Abstract

Alcohol possesses complex sensory attributes that are first detected by the body via sensory receptors and afferent fibers that promptly transmit signals to brain areas involved in mediating ingestive motivation, reinforcement, and addictive behavior. Given that the chemosensory cues accompanying alcohol consumption are among the most intimate, consistent, and immediate predictors of alcohol's postabsorptive effects, with experience these stimuli also gain powerful associative incentive value to elicit craving and related physiologic changes, maintenance of ongoing alcohol use, and reinstatement of drug seeking after periods of abstinence. Despite the above, preclinical research has traditionally dichotomized alcohol's taste and postingestive influences as independent regulators of motivation to drink. The present review summarizes current evidence regarding alcohol's ability to directly activate peripheral and central oral chemosensory circuits, relevance for intake of the drug, and provides a framework for moving beyond a dissociation between the sensory and postabsorptive effects of alcohol to understand their neurobiological integration and significance for alcohol addiction.

Indexed as

Alcohol DrinkingAnimalsEthanolHumansLimbic SystemMotivationSensationEthanolAddictionAlcoholChemosensoryEthanolReinforcementTasteTrigeminal

Identifiers

PMID25304192
PMCPMC4388769
OpenAlexW2019420422

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.