ReviewCurrent hypertension reports2014
Polycystic ovary syndrome as a paradigm for prehypertension, prediabetes, and preobesity.
Review in Current hypertension reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Amount, Distribution and Dysfunction of Body Fat as Determinants of Female Gonadal Dysfunction: From Functional Hypothalamic Amenorrhea to the Polycystic Ovary Syndrome
Pathogenesis of Functional Hyperandrogenism in Women With Type 1 Diabetes Mellitus: From Genetic-molecular Mechanisms to Clinical Phenotype.
Who cites it
14 citing papers in PubMed, 41 citations in OpenAlex.
- The impact of 1-hour plasma glucose on the metabolic characteristics and pregnancy outcomes in polycystic ovary syndrome.Nutrition & diabetes · 2026Article
- Differences in clinical characteristics and cardiovascular disease risk prediction among Chinese women with polycystic ovary syndrome phenotypes: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Characteristics and risk factors associated with developing prediabetes in Saudi Arabia.Annals of medicine · 2024Article
- The association between gut microbiome and PCOS: evidence from meta-analysis and two-sample mendelian randomization.Frontiers in microbiology · 2023Article
- The prevalence and phenotypic manifestations of polycystic ovary syndrome (PCOS) among infertile Sudanese women: a cross-sectional study.BMC women's health · 2022Article
- The impact of depression, self-esteem, and body image on sleep quality in patients with PCOS: a cross-sectional study.Sleep & breathing = Schlaf & Atmung · 2020Article
- Exploration of the Relationship Between Gut Microbiota and Polycystic Ovary Syndrome (PCOS): a Review.Geburtshilfe und Frauenheilkunde · 2020Article
- Heat therapy improves glucose tolerance and adipose tissue insulin signaling in polycystic ovary syndrome.American journal of physiology. Endocrinology and metabolism · 2019Article
- Gender, hyperandrogenism and vitamin D deficiency related functional and morphological alterations of rat cerebral arteries.PloS one · 2019Article
- Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters.BMC genomics · 2018Article
- Meta-inflammation and cardiometabolic disease in obesity: Can heat therapy help?Temperature (Austin, Tex.) · 2018Review
- Association of IL-1β, IL-1Ra and FABP1 gene polymorphisms with the metabolic features of polycystic ovary syndrome.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2017Article
- Physical Properties of Blood Are Altered in Young and Lean Women with Polycystic Ovary Syndrome.PloS one · 2016Article
- Polycystic ovary syndrome: clinical implication in perimenopause.Przeglad menopauzalny = Menopause review · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The polycystic ovary syndrome (PCOS) is a hyperandrogenic disorder affecting 5-10 % of premenopausal women. These patients gather multiple cardiovascular risk factors from early ages. Hence, PCOS is currently considered a paradigm of cardiometabolic disease. Research about its pathogenesis has grown over the last years, covering from the potential fetal developmental programming to the molecular basis of adipose tissue dysfunction, insulin resistance, inflammation, oxidative stress, sympathetic hyperactivity, and endothelial dysfunction. All these abnormalities put these patients at an increased risk of vascular events. Thus, practitioners attending these women must have a broad pathophysiological knowledge of PCOS. We here review recent scientific insights about its cardiometabolic phenotype focusing on the pathogenesis of obesity, type 2 diabetes mellitus, and hypertension. We emphasize that a diagnosis of PCOS, especially if accompanied by excess weight, must be followed by a complete and periodical cardiometabolic evaluation and by the aggressive management of the abnormalities identified, with the aim of preventing future cardiovascular morbidity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.