ReviewCurrent HIV/AIDS reports2014
Optimizing ART adherence: update for HIV treatment and prevention.
Review in Current HIV/AIDS reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04240210 (SymITA), which is not on this map. Cited by 46 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SymITA: Switch to DRV/COB/FTC/TAF From Integrase Containing Regimens to Evaluate Changes in Tolerability/Adherence
Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Adherence to option B + antiretroviral therapy and associated factors in pregnant and breastfeeding women in Sub-Saharan Africa: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Antiretroviral Concentration in Hair as a Measure for Antiretroviral Medication Adherence: A Systematic Review of Global Literature.AIDS and behavior · 2020Pooled it
- Real-time Feedback to Improve HIV Treatment Adherence in Pregnant and Postpartum Women in Uganda: A Randomized Controlled Trial.AIDS and behavior · 2022Trial
- Trial
- Reliability, validity and measurement invariance of the Simplified Medication Adherence Questionnaire (SMAQ) among HIV-positive women in Ethiopia: a quasi-experimental study.BMC public health · 2020Trial
- Empowering Lay-Counsellors with Technology: Masivukeni, a Standardized Multimedia Counselling Support Tool to Deliver ART Counselling.AIDS and behavior · 2018Trial
- Trial
- Design of the HPTN 065 (TLC-Plus) study: A study to evaluate the feasibility of an enhanced test, link-to-care, plus treat approach for HIV prevention in the United States.Clinical trials (London, England) · 2017Trial
- Sustained viral suppression among people with HIV in the era of Undetectable = Untransmittable (U = U) in Australia.AIDS (London, England) · 2026Article
- Cultural adaptation and psychometric validation of the Amharic adherence barriers questionnaire for HIV patients on antiretroviral therapy in Ethiopia.Scientific reports · 2026Article
- Modeling the Public Health Impact of Improved Antiretroviral Therapy Restart Patterns Among People with HIV Who Have Discontinued Treatment.Journal of health economics and outcomes research · 2026Article
- Article
- Examining the association between medication adherence trajectories and disease-specific clinical outcomes: An analysis focusing on the drug classes included in Part D quality bonus payments.Journal of managed care & specialty pharmacy · 2025Article
- Latent Healthcare Stigma Profiles and Their Association With Human Immunodeficiency Virus (HIV) Treatment and Care Outcomes Among Women With HIV in the United States: An Intersectional Analysis.Open forum infectious diseases · 2025Article
- Article
- Robustness of viral load over CD4 cell count in measuring the quality of life of people with HIV at second line regimen in Amhara region.Scientific reports · 2025Article
- 'Those sessions open[ed] our eyes and our minds': participant acceptability and satisfaction with a gender-focused HIV and substance use risk-reduction intervention on alcohol use, HIV treatment, and sexual behaviour among women in South Africa.Health education research · 2025Article
- Identifying barriers and facilitators to psychosocial care for people living with HIV in Ireland: a mixed methods study.BMC public health · 2025Article
- Community-engaged adaptation and pilot testing of a mental health and substance use screening and referral process in HIV pre-exposure prophylaxis (PrEP) care in the Southern USA.PLOS mental health · 2025Article
- Association of ART regimen and adherence to viral suppression: an observational study of a clinical population of people with HIV.AIDS research and therapy · 2024Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Optimal adherence to antiretroviral therapy (ART) is central to achieving viral suppression and positive health outcomes in HIV-infected individuals. Virally suppressed individuals can also reduce the risk of HIV transmission to uninfected partners. Hence, adherence to ART has become both an HIV treatment and an HIV prevention strategy. However, achieving optimal ART adherence can be challenging, especially over the long term. It is increasingly important for clinicians and researchers to be abreast of the most recent developments in the field as new biomedical approaches to treatment emerge and as guidelines for the use of pre-exposure prophylaxis (PrEP) are disseminated to providers serving HIV affected populations. Several reviews have described numerous ART adherence interventions that have been developed and/or tested with the most recent review including literature up to 2012. To augment the literature, we present a review of ART adherence interventions from 2013 to the present. We included peer-reviewed journals as well as abstracts from two key conferences.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.