ArticleSurgical endoscopy2015
Surgical site infection after laparoscopic and open appendectomy: a multicenter large consecutive cohort study.
Article in Surgical endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Global incidence of surgical site infection after appendectomy: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- Diagnosis and management of acute appendicitis. EAES consensus development conference 2015.Surgical endoscopy · 2016Guideline
- Single-instrument intracorporeal ligation versus polymer clip closure of the appendiceal stump in laparoscopic appendectomy: a prospective randomized study.BMC surgery · 2026Trial
- Is it necessary to use specimen retrieval bag for reducing surgical site infection in laparoscopic appendectomy?A randomized controlled trial.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023Trial
- Acute Appendicitis: Still a Surgical Disease? Results from a Propensity Score-Based Outcome Analysis of Conservative Versus Surgical Management from a Prospective Database.World journal of surgery · 2017Trial
- Surgical Site Infections After Laparotomy in a Tertiary Referral Hospital in Kenya: Incidence and Risk Factors.World journal of surgery · 2026Article
- The advantages and intraoperative management of the laparoscopic approach in perforated appendicitis.Journal of minimal access surgery · 2026Article
- Postoperative Infections After Appendectomy for Acute Appendicitis: The Surgeon's Checklist.Antibiotics (Basel, Switzerland) · 2025Review
- Post appendectomy complications and associated factors among children in Amhara region, ethiopia: Multi-center retrospective follow up study.Langenbeck's archives of surgery · 2025Article
- Article
- The Impact of Obesity on Perioperative Outcomes for Children Undergoing Appendectomy for Acute Appendicitis: A Systematic Review.Journal of clinical medicine · 2023Review
- Development and validation of risk prediction score for incisional surgical site infection after appendectomy.Updates in surgery · 2021Article
- Prevalence and Predictive Factors for Nosocomial Infection in the Military Hospitals: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2021Review
- Appendectomy in Patients with Morbid Obesity: Laparoscopic versus Conventional Technique.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Artificial Intelligence-Based Multimodal Risk Assessment Model for Surgical Site Infection (AMRAMS): Development and Validation Study.JMIR medical informatics · 2020Article
- Bacterial culture and antibiotic susceptibility in patients with acute appendicitis.International journal of colorectal disease · 2018Article
- Prospective Observational Study on acute Appendicitis Worldwide (POSAW).World journal of emergency surgery : WJES · 2018Observational
- Laparoscopic Appendectomy: Risk Factors for Postoperative Intraabdominal Abscess.World journal of surgery · 2017Article
- Pediatric appendicitis: state of the art review.Pediatric surgery international · 2017Review
- Incidence and Etiology of Surgical Site Infections in Appendectomies: A 3-Year Prospective Study.Oman medical journal · 2017Article
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic appendectomy (LA) has been rapidly applied worldwide recently. The issue of surgical site infection (SSI) after appendectomy needs to be re-investigated and analyzed along with this trend. This study aimed to identify risk factors of SSI after appendectomy in recent years.
methodsThis retrospective study was conducted among patients with acute appendicitis who underwent either laparoscopic or open appendectomy (OA) at 7 general hospitals in China from 2010 to 2013. The incidence of SSI, classified as incisional SSI and organ/space SSI, was investigated. A multivariate logistic regression model was used to assess independent risk factors associated with overall, incisional, and organ/space SSI, respectively.
resultsAmong 16,263 consecutive patients, 3,422 (21.0 %) and 12,841 (79.0 %) patients underwent LA and OA, respectively. The incidences of overall, incisional, and organ/space SSI were 6.2, 3.7, and 3.0 %, respectively. The proportion of LAs among both procedures increased yearly from 5.3 to 46.5 %, while the incidences of overall and incisional SSI after appendectomy simultaneously decreased yearly from 9.6 to 4.5 % and from 6.7 to 2.2 %, respectively. In comparison with OA, LA was associated with lower incidences of overall and incisional SSI (4.5 vs 6.7 %, P < 0.001; and 1.9 vs 4.2 %, P < 0.001), but a similar incidence of organ/space SSI (3.0 vs 3.0 %, P = 0.995). After multivariate logistic regression analyses were performed, LA was found to be independently associated with a decrease in development of overall SSI [odds ratio (95 % confidence interval) OR (95 % CI), 1.24 (1.03-1.70); P = 0.04] or incisional SSI [OR (95 % CI), 1.32 (1.10-1.68); P = 0.01].
conclusionWith the increasing application trends of laparoscopic procedure, the incidence of SSI after appendectomy declined accordingly. Compared with OA, LA was independently associated with a significantly lower incidence of incisional SSI, but a similar incidence of organ/space SSI.
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