ArticleSeminars in thrombosis and hemostasis2014
Thrombosis: a major contributor to global disease burden.
Article in Seminars in thrombosis and hemostasis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 3 of them syntheses that pooled it.
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Who cites it
73 citing papers in PubMed, 3 syntheses or guidelines pooled it, 140 citations in OpenAlex.
- Machine Learning for Predicting Venous Thromboembolism After Joint Arthroplasty: Systematic Review of Clinical Applicability and Model Performance.JMIR medical informatics · 2026Pooled it
- Pooled it
- Interventions for implementation of thromboprophylaxis in hospitalized patients at risk for venous thromboembolism.The Cochrane database of systematic reviews · 2018Pooled it
- A simplified nomogram for predicting deep vein thrombosis: development in NHANES and retrospective single-center external validation.Annals of medicine · 2026Article
- Selective Thrombin Modulation by AYA1809002: Stability and On-Demand Reversal of an Exosite I-Targeting Aptamer.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Mechanical thrombectomy improves left ventricular filling in intermediate-high risk pulmonary embolism: the role of ventricular interdependence.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Effects of Cocoa Extract and Multivitamin Supplementation on Venous Thromboembolism in the COSMOS Trial.Thrombosis and haemostasis · 2026Article
- Sensitivity analysis of factors in a microfluidics CFD model of coagulation and cardiac applications.Biomechanics and modeling in mechanobiology · 2026Article
- Purification, characterization, and anticoagulant mechanism of an anticoagulant protein from marineFrontiers in microbiology · 2026Article
- Observational
- Article
- Real-World Patterns and Outcomes of Anticoagulation Therapy in Pulmonary Embolism: An Observational Dual-Centre Registry Analysis.Journal of cardiovascular development and disease · 2025Article
- Comprehensive review of pulmonary embolism imaging: past, present and future innovations in computed tomography (CT) and other diagnostic techniques.Japanese journal of radiology · 2025Review
- Venous thromboembolisms and stroke risk in patients with atrial fibrillation: a nationwide cohort study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- Nanomedicine in cardiovascular and cerebrovascular diseases: targeted nanozyme therapies and their clinical potential and current challenges.Journal of nanobiotechnology · 2025Review
- Comparison of half-dose alteplase and LMWH in intermediate-high risk pulmonary embolism: a single-center observational study.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
- Article
- Soluble ST2 as a Biomarker for Predicting Right Ventricular Dysfunction in Acute Pulmonary Embolism.Journal of clinical medicine · 2024Article
- Gender-specific relationships between hyperuricemia and idiopathic deep venous thrombosis in the Chinese population: a case‒control study.Thrombosis journal · 2024Article
- Decoding Pulmonary Embolism: Pathophysiology, Diagnosis, and Treatment.Biomedicines · 2024Review
13 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
14 authors at 11 institutions in 9 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thrombosis is a common pathology underlying ischemic heart disease, ischemic stroke, and venous thromboembolism (VTE). The Global Burden of Disease Study 2010 (GBD 2010) documented that ischemic heart disease and stroke collectively caused one in four deaths worldwide. GBD 2010 did not report data for VTE as a cause of death and disability. We performed a systematic review of the literature on the global disease burden due to VTE in low-, middle-, and high-income countries. Studies from Western Europe, North America, Australia, and Southern Latin America (Argentina) yielded consistent results with annual incidences ranging from 0.75 to 2.69 per 1,000 individuals in the population. The incidence increased to between 2 and 7 per 1,000 among those 70 years of age or more. Although the incidence is lower in individuals of Chinese and Korean ethnicity, their disease burden is not low because of population aging. VTE associated with hospitalization was the leading cause of disability-adjusted-life-years (DALYs) lost in low- and middle-income countries, and second in high-income countries, responsible for more DALYs lost than nosocomial pneumonia, catheter-related blood stream infections, and adverse drug events. VTE causes a major burden of disease across low-, middle-, and high-income countries. More detailed data on the global burden of VTE should be obtained to inform policy and resource allocation in health systems, and to evaluate if improved utilization of preventive measures will reduce the burden.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.