Evidence map›Paper›PMID 25302678›Full record

SynthesisPloS one2014

Systematic review of clinical practice guidelines related to multiple sclerosis.

Jia Guo, Chuang Cheng, Weiping Yan, Guanghui Xu, Jinzhou Feng, Tianzhu Wang, Cindy Si Chen, Xinyue Qin

Abstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jia GuoDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China.
Chuang ChengDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China.
Weiping YanDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China.
Guanghui XuDepartment of Neurology, The Third People's Hospital of Chengdu, Chengdu, PR China.
Jinzhou FengDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China.
Tianzhu WangDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China.
Cindy Si ChenDepartment of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America.
Xinyue QinDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh quality clinical practice guidelines (CPGs) can provide clinicians with explicit recommendations on how to manage health conditions and bridge the gap between research and clinical practice. Unfortunately, the quality of CPGs for multiple sclerosis (MS) has not been evaluated.

objectiveTo evaluate the methodological quality of CPGs on MS using the AGREE II instrument.

methodsAccording to the inclusion and exclusion criteria, we searched four databases and two websites related to CPGs, including the Cochrane library, PubMed, EMBASE, DynaMed, the National Guideline Clearinghouse (NGC), and Chinese Biomedical Literature database (CBM). The searches were performed on September 20th 2013. All CPGs on MS were evaluated by the AGREE II instrument. The software used for analysis was SPSS 17.0.

resultsA total of 27 CPGs on MS met inclusion criteria. The overall agreement among reviews was good or substantial (ICC was above 0.70). The mean scores for each of all six domains were presented as follows: scope and purpose (mean ± SD: 59.05 ± 16.13), stakeholder involvement (mean ± SD: 29.53 ± 17.67), rigor of development (mean ± SD: 31.52 ± 21.50), clarity of presentation (mean ± SD: 60.39 ± 13.73), applicability (mean ± SD: 27.08 ± 17.66), editorial independence (mean ± SD: 28.70 ± 22.03).

conclusionsThe methodological quality of CPGs for MS was acceptable for scope, purpose and clarity of presentation. The developers of CPGs need to pay more attention to editorial independence, applicability, rigor of development and stakeholder involvement during the development process. The AGREE II instrument should be adopted by guideline developers.

Indexed as

Practice Guidelines as TopicHumansLibraries, DigitalMultiple SclerosisPubMed

Identifiers

PMID25302678
PMCPMC4193735

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.