ArticleJournal of clinical and diagnostic research : JCDR2014
Diagnostic value of bone marrow aspiration and biopsy in routine hematology practice.
Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 40 citations in OpenAlex.
- Effects of fixation and demineralization on immunohistochemical assessment of canine bone marrow.Veterinary pathology · 2026Article
- Hematopoietic Niche Hijacking in Bone Metastases: Roles of Megakaryocytes, Erythroid Lineage Cells, and Perivascular Stromal Subsets.Biomedicines · 2026Review
- Rapid, Point-of-Care Bone Marrow Aspirate Adequacy Assessment Via Deep Ultraviolet Microscopy.Laboratory investigation; a journal of technical methods and pathology · 2025Article
- Advancements in Hematologic Malignancy Detection: A Comprehensive Survey of Methodologies and Emerging Trends.TheScientificWorldJournal · 2025Review
- Artificial Intelligence-Assisted Diagnostic Cytology and Genomic Testing for Hematologic Disorders.Cells · 2023Review
- Etiological Profiles of Patients With Thrombocytopenia in Central India: A Tertiary Centre Study.Cureus · 2022Article
- A study of patient-reported pain during bone marrow aspiration and biopsy using local anesthesia alone compared with local anesthesia with intravenous midazolam coadministration at a tertiary academic hospital in South Africa.Health science reports · 2022Article
- Bone marrow aspiration and biopsy: techniques and practice implications.Skeletal radiology · 2022Review
- Neoteric Algorithm Using Cell Population Data (VCS Parameters) as a Rapid Screening Tool for Haematological Disorders.Diagnostics (Basel, Switzerland) · 2021Article
- A Comparative Study of Bone Marrow Squash and Wedge Aspiration Smears.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2021Article
- Efficacy and safety of bone marrow aspiration and biopsy using fluoroscopic guidance and a drill-powered needle: clinical experience from 775 cases.European radiology · 2020Article
- Review
- Peripheral Smear Review and Bone Marrow Biopsy Correlation.Journal of clinical and diagnostic research : JCDR · 2017Article
- White blood cell differential count of maturation stages in bone marrow smear using dual-stage convolutional neural networks.PloS one · 2017Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe bone marrow is frequently involved in variety of cases presenting with hematological and non-hematological disorders, which are diagnosed by two separate but interrelated techniques such as bone marrow aspiration (BMA) and bone marrow biopsy (BMB).
aimThis study was aimed to assess the diagnostic value of the BMA and BMB and role of both the procedures to reach final diagnosis when done simultaneously. SETTINGS AND
designIt was a prospective study. The findings of BMA smears were correlated with BMB sections and data obtained was analysed. MATERIALS AND
methodsBMA and BMB were performed on 50 patients. Criteria of inclusion included the main indications for performing this procedure, the availability of full medical records and patient consent. The patients had a male to female sex ratio of 1.6:1 and a wide age range from 4 years to 74 years.
resultsIn the present study, the main indications for bone marrow examination were categorized. Out of 50 cases studied, in 23 cases, a strong positive correlation between BMA and BMB was noted. However, it was found that in the cases of aplastic anaemia, different phases of myeloproliferative neoplasm (MPN), multiple myeloma, tubercular granulomas and hemato-lymphoid neoplasm, involvement of the marrow was detected better in bone marrow biopsies.
conclusionThe study concludes that preparations of aspirate and trephine biopsy are easy, rapid and complementary to each other in majority of the lesions. The advantage of both the procedures done together enabled us to study the cytomorphology of the cells along with the pattern of distribution of the cells depending on the cases, hence help in making the diagnosis accurately.
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