Evidence map›Paper›PMID 25302115›Full record

ArticleJournal of obesity2014

Importance of android/gynoid fat ratio in predicting metabolic and cardiovascular disease risk in normal weight as well as overweight and obese children.

Lennie Samsell, Michael Regier, Cheryl Walton, Lesley Cottrell

Abstract read
In one paragraph

Article in Journal of obesity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. ANTHROPOMETRY AND CLUSTERED CARDIOMETABOLIC RISK FACTORS IN YOUNG PEOPLE: A SYSTEMATIC REVIEW.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo
    Pooled it
  4. Trial
  5. Endocrinopathies, Bone Health, and Insulin Resistance in Patients with Fanconi Anemia after Hematopoietic Cell Transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2016
    Trial
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  16. Adiposity and cardiac autonomic function in children with a family history of obesity.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Observational
  17. Article
  18. Determination of body composition by dual x-ray absorptiometry in persons with haemophilia.Haemophilia : the official journal of the World Federation of Hemophilia · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lennie SamsellDepartment of Pediatrics, School of Medicine, West Virginia University, Morgantown, WV 9214, USA.ORCID 0000-0002-6824-4234
Michael RegierDepartment of Biostatistics, School of Public Health, West Virginia University, Morgantown, WV 6057, USA.
Cheryl WaltonDepartment of Pediatrics, School of Medicine, West Virginia University, Morgantown, WV 9214, USA.ORCID 0000-0002-5573-9174
Lesley CottrellDepartment of Pediatrics, School of Medicine, West Virginia University, Morgantown, WV 9214, USA.ORCID 0000-0001-9799-9727

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have shown that android or truncal obesity is associated with a risk for metabolic and cardiovascular disease, yet there is evidence that gynoid fat distribution may be protective. However, these studies have focused on adults and obese children. The purpose of our study was to determine if the android/gynoid fat ratio is positively correlated with insulin resistance, HOMA2-IR, and dislipidemia in a child sample of varying body sizes. In 7-13-year-old children with BMI percentiles ranging from 0.1 to 99.6, the android/gynoid ratio was closely associated with insulin resistance and combined LDL + VLDL-cholesterol. When separated by sex, it became clear that these relationships were stronger in boys than in girls. Subjects were stratified into BMI percentile based tertiles. For boys, the android/gynoid ratio was significantly related to insulin resistance regardless of BMI tertile with and LDL + VLDL in tertiles 1 and 3. For girls, only LDL + VLDL showed any significance with android/gynoid ratio and only in tertile 2. We conclude that the android/gynoid fat ratio is closely associated with insulin resistance and LDL + VLDL-, "bad," cholesterol in normal weight boys and may provide a measurement of metabolic and cardiovascular disease risk in that population.

Indexed as

Absorptiometry, PhotonAdolescentBody CompositionBody Fat DistributionCardiovascular DiseasesChildFemaleHumansInsulin ResistanceMaleMetabolic SyndromePediatric ObesityPredictive Value of TestsSeverity of Illness IndexThinness

Identifiers

PMID25302115
PMCPMC4181515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.