ArticleJournal of the International AIDS Society2014
Disengagement of HIV-positive pregnant and postpartum women from antiretroviral therapy services: a cohort study.
Article in Journal of the International AIDS Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
88 citing papers in PubMed, 3 syntheses or guidelines pooled it, 133 citations in OpenAlex.
- Vulnerability and non-adherence to treatment in cisgender women living with HIV/AIDS: a scoping review (2000-2024).Archives of public health = Archives belges de sante publique · 2026Pooled it
- Attrition of HIV-exposed infants from early infant diagnosis services in low- and middle-income countries: a systematic review and meta-analysis.Journal of the International AIDS Society · 2018Pooled it
- A systematic review of interventions to improve postpartum retention of women in PMTCT and ART care.Journal of the International AIDS Society · 2016Pooled it
- Effects of a Home-Based Intervention on HIV Prevention Health Behaviors in Pregnant/Postpartum Kenyan Women: Estimating Moderating Effects of Depressive Symptoms.AIDS and behavior · 2021Trial
- Retention in HIV Care Among HIV-Seropositive Pregnant and Postpartum Women in Uganda: Results of a Randomized Controlled Trial.AIDS and behavior · 2020Trial
- Population-level viral suppression among pregnant and postpartum women in a universal test and treat trial.AIDS (London, England) · 2020Trial
- Exclusive breast-feeding promotion among HIV-infected women in South Africa: an Information-Motivation-Behavioural Skills model-based pilot intervention.Public health nutrition · 2017Trial
- Uptake and retention in HIV care among pregnant and postpartum women living with HIV under different eras of vertical transmission prevention policies in sub-Saharan Africa: a systematic review and meta-analysis.medRxiv : the preprint server for health sciences · 2026Article
- Perspectives on enhancing peer support services for mothers living with HIV in Kenya: A qualitative assessment of Mentor Mothers and the mothers they serve.PLOS global public health · 2026Article
- Using interactive SMS support groups to prevent mother-to-child HIV transmission in South Africa: a qualitative analysis of social and psychological benefits.SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance · 2025Article
- Development and Validation of a Novel Risk Calculator to Predict Sub-optimal HIV Outcomes Among Pregnant and Postpartum Women with HIV in Kenya.AIDS and behavior · 2025Article
- Health System Factors Influencing the Integration of Pre-Exposure Prophylaxis into Antenatal and Postnatal Clinic Services in Cape Town, South Africa.Global health, science and practice · 2024Article
- "I Have to Stand Up on My Own and Do the Best I Can for My Kids"AIDS and behavior · 2024Article
- Support, not blame: safe partner disclosure among women diagnosed with HIV late in pregnancy in South Africa and Uganda.AIDS research and therapy · 2024Article
- Experiences of transfer of care among postpartum women living with HIV attending primary healthcare services in South Africa.Global public health · 2024Article
- Womandla Health: development and rationale of a behavioral intervention to support HIV treatment adherence among postpartum women in South Africa.BMC women's health · 2023Article
- Integration of HIV pre-exposure prophylaxis (PrEP) services for pregnant and breastfeeding women in eight primary care clinics: results of an implementation science study.Research square · 2023Article
- Triple Benefit: Impact of an Integrated Early Childhood Development and PMTCT Intervention on ART Outcomes Among Mothers Living with HIV and Infants in Malawi-An Endline Evaluation.AIDS and behavior · 2023Observational
- Article
- Incidence and predictors of loss to follow-up among pregnant and lactating women in the Option B+ PMTCT program in Northwestern Ethiopia: a seven-year retrospective cohort study.Frontiers in global women's health · 2023Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRecent international guidelines call for expanded access to triple-drug antiretroviral therapy (ART) in HIV-positive women during pregnancy and postpartum. However, high levels of non-adherence and/or disengagement from care may attenuate the benefits of ART for HIV transmission and maternal health. We examined the frequency and predictors of disengagement from care among women initiating ART during pregnancy in Cape Town, South Africa.
methodsWe used routine medical records to follow-up pregnant women initiating ART within prevention of mother-to-child transmission of HIV services in Cape Town, South Africa. Outcomes assessed through six months postpartum were (1) disengagement (no attendance within 56 days of a scheduled visit) and (2) missed visits (returning to care 14-56 days late for a scheduled visit).
resultsA total of 358 women (median age, 28 years; median gestational age, 26 weeks) initiated ART during pregnancy. By six months postpartum, 24% of women (n=86) had missed at least one visit and an additional 32% (n=115) had disengaged from care; together, 49% of women had either missed a visit or had disengaged by six months postpartum. Disengagement was more than twice as frequent postpartum compared to in the antenatal period (6.2 vs. 2.4 per 100 woman-months, respectively; p<0.0001). In a proportional hazards model, later gestational age at initiation (HR: 1.04; 95% CI: 1.00-1.07; p=0.030) and being newly diagnosed with HIV (HR: 1.57; 95% CI: 1.07-2.33; p=0.022) were significant predictors of disengagement after adjusting for patient age, starting CD4 cell count and site of ART initiation.
conclusionsThese results demonstrate that missed visits and disengagement from care occur frequently, particularly post-delivery, among HIV-positive women initiating ART during pregnancy. Women who are newly diagnosed with HIV may be particularly vulnerable and there is an urgent need for interventions both to promote retention overall, as well as targeting women newly diagnosed with HIV during pregnancy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.