ArticleBlood2014
Macrophages shine bright.
Article in Blood, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Monocyte Recruitment for Vascular Tissue Regeneration.Advanced healthcare materials · 2022Article
Corrections and comments
- Comment on
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this issue of Blood, Iqbal et al created a novel mouse model with a strong expression of green fluorescence protein (GFP) in monocytes, tissue resident macrophages, and inflammatory macrophages, and may provide an important tool for future studies focusing on macrophage biology. Several transgenic mice with expression of fluorescent proteins in myeloid cells exist, among them the CCR2-RFP and the CX3CR1GFP mouse. However, both of these mice have several limitations: they are knock-in constructs under control of chemokine receptors with potential effects on monocyte mobilization from the bone marrow, recruitment to sites of inflammation, or survival. Alteration of chemokine receptor expression during macrophage differentiation may affect expression of fluorescent proteins and thus render macrophages nonfluorescent.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.