Evidence map›Paper›PMID 25301208›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015

Improvements in HIV care engagement and viral load suppression following enrollment in a comprehensive HIV care coordination program.

Mary K Irvine, Stephanie A Chamberlin, Rebekkah S Robbins, Julie E Myers, Sarah L Braunstein, Beau J Mitts, Graham A Harriman, Fabienne Laraque, Denis Nash

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03628287 (Program Refinements to Optimize Model Impact and Scalability Based on Evidence), which is not on this map. Cited by 63 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03628287 nacompletednot on this mapstarted 2018, after this paper: background citation

Program Refinements to Optimize Model Impact and Scalability Based on Evidence

TypeinterventionalSponsorCity University of New York, School of Public HealthRan2018 to 2023Enrolled960ConditionsHivArmsRevised Care Coordination Program, Original Care Coordination Program
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  20. Client-Centered Care Coordination (C4Sexuality research & social policy : journal of NSRC : SR & SP · 2022
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Mary K IrvineBureau of HIV/AIDS Prevention and Control, New York City Department of Health and Mental Hygiene.
Stephanie A ChamberlinBureau of HIV/AIDS Prevention and Control, New York City Department of Health and Mental Hygiene.
Rebekkah S RobbinsBureau of HIV/AIDS Prevention and Control, New York City Department of Health and Mental Hygiene.
Julie E MyersBureau of HIV/AIDS Prevention and Control, New York City Department of Health and Mental Hygiene Division of Infectious Diseases, Department of Medicine, Columbia University Medical Center.
Sarah L BraunsteinBureau of HIV/AIDS Prevention and Control, New York City Department of Health and Mental Hygiene.
Beau J MittsBureau of HIV/AIDS Prevention and Control, New York City Department of Health and Mental Hygiene.
Graham A HarrimanBureau of HIV/AIDS Prevention and Control, New York City Department of Health and Mental Hygiene.
Fabienne Laraque
Denis NashSchool of Public Health Hunter College, The City University of New York, New York.

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
HIV care coordination: comparative effectiveness, outcome determinants and costsR01MH101028 · NIMH · HUNTER COLLEGE · PI IRVINE, MARY KATHRYN, NASH, DENIS · 2013 to 2017
$3.1M
NIMH NIH HHS P30 MH043520NIMH NIH HHS R01 MH101028NIMH NIH HHS R01 MH101028-01A1
6 · The paper itself

Abstract

backgroundSubstantial evidence gaps remain regarding human immunodeficiency virus (HIV) intervention strategies that improve engagement in care (EiC) and viral load suppression (VLS). We assessed EiC and VLS before and after enrollment in a comprehensive intervention for persons at risk of poor HIV care outcomes.

methodsNew York City's Ryan White Part A HIV Care Coordination Program (CCP), launched at 28 agencies in 2009, applies multiple strategies to promote optimal utilization of medical and social services. Using laboratory test records from an HIV surveillance registry, we examined pre-post outcomes among 3641 CCP clients enrolled before April 2011. For the year before and after enrollment, we assessed EiC (defined as ≥2 tests, ≥90 days apart, with ≥1 in each half-year) and VLS (defined as viral load [VL] ≤200 copies/mL on latest VL test in the second half of the year). We estimated relative risks (RRs), comparing pre- and postenrollment proportions achieving EiC and VLS.

resultsAmong newly diagnosed clients, 90.5% (95% confidence interval [CI], 87.9%-93.2%) and 66.2% (95% CI, 61.9%-70.6%) achieved EiC and VLS, respectively. Among previously diagnosed clients, EiC increased from 73.7% to 91.3% (RR = 1.24; 95% CI, 1.21-1.27) and VLS increased from 32.3% to 50.9% (RR = 1.58; 95% CI, 1.50-1.66). Clients without evidence of HIV care during the 6 months preenrollment contributed most to overall improvements. Pre-post improvements were robust, retaining statistical significance within most sociodemographic and clinical subgroups, and in 89% (EiC) and 75% (VLS) of CCP agencies.

conclusionsClients in comprehensive HIV care coordination for persons with evident barriers to care showed substantial and consistent improvement in short-term outcomes.

Indexed as

Comprehensive Health CareViral LoadAdultAgedCD4 Lymphocyte CountCohort StudiesFemaleHIV InfectionsHumansMaleMiddle AgedNew York CityPublic Health AdministrationRetrospective StudiesTreatment OutcomeYoung Adultimplementation scienceintervention effectivenessoutcomes evaluationpublic health surveillanceRyan White

Identifiers

PMID25301208
PMCPMC4296107

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.