ArticleAJNR. American journal of neuroradiology2015
Diffusivity measurements differentiate benign from malignant lesions in patients with peripheral neuropathy or plexopathy.
Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Imaging of non-neurogenic peripheral nerve malignancy-a case series and systematic review.Skeletal radiology · 2021Pooled it
- A case of intrapulmonary schwannoma in a patient with rectal carcinoma: A case report and literature review.Radiology case reports · 2026Article
- Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases.Oncology letters · 2026Article
- Advanced Imaging of the Peripheral Nerves, From theAJR. American journal of roentgenology · 2024Review
- Case report: Brachial plexopathy caused by malignant peripheral nerve sheath tumor and review of the literature.Frontiers in neurology · 2023Article
- Neoplastic nerve lesions.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Review
- Adrenal schwannoma: a case report.BJR case reports · 2020Article
- Diffusion Tensor Imaging of the Brachial Plexus: A Comparison between Readout-segmented and Conventional Single-shot Echo-planar Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2019Article
- Utility of MRI neurography in neurofibromatosis type I: Case example and review of MRI neurography literature.Surgical neurology international · 2019Article
- Demystifying MR Neurography of the Lumbosacral Plexus: From Protocols to Pathologies.BioMed research international · 2018Review
- Recent advances in magnetic resonance neuroimaging of lumbar nerve to clinical applications: A review of clinical studies utilizing Diffusion Tensor Imaging and Diffusion-weighted magnetic resonance neurography.Spine surgery and related research · 2017Review
- Large Cervical Vagus Nerve Tumor in a Patient with Neurofibromatosis Type 1 Treated with Gross Total Resection: Case Report and Review of the Literature.Journal of brachial plexus and peripheral nerve injury · 2016Review
- Differentiation of MPNSTs from benign neurofibromas in neurofibromatosis patients using ADC and SUV biomarkers in children and young adults.Current problems in diagnostic radiologyArticle
- A Rare Case of Malignant Peripheral Nerve Sheath Tumour of the Brachial Plexus with a Diagnostic Dilemma.Journal of the West African College of SurgeonsArticle
- A Case of Suspected Breast Cancer Metastasis to Brachial Plexus Detected by Magnetic Resonance Neurography.Case reports in oncologyArticle
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposePeripheral nerve disorders caused by benign and malignant primary nerve sheath tumors, infiltration or compression of nerves by metastatic disease, and postradiation neuritis demonstrate overlapping features on conventional MR imaging but require vastly different therapeutic approaches. We characterize and compare diffusivities of peripheral nerve lesions in patients undergoing MR neurography for peripheral neuropathy or brachial or lumbosacral plexopathy. MATERIALS AND
methodsTwenty-three patients, referred for MR neurography at our institution between 2003 and 2009 for a peripheral mononeuropathy or brachial or lumbosacral plexopathy and whose examinations included DWI, received a definitive diagnosis, based on biopsy results or clinical and imaging follow-up, for a masslike or infiltrative peripheral nerve or plexus lesion suspicious for tumor. Mean ADC values were determined within each lesion and compared across 3 groups (benign lesions, malignant lesions, and postradiation changes).
resultsBoth ANOVA and Kruskal-Wallis tests demonstrated a statistically significant difference in ADC values across the 3 groups (P = .000023, P = .00056, respectively). Post hoc pair-wise comparisons showed that the ADC within malignant tumors differed significantly from that within benign tumors and postradiation changes. ADC within benign tumors and postradiation changes did not differ significantly from each other.
conclusionsDWI may be highly effective for the differentiation of benign from malignant peripheral nerve masslike or infiltrative lesions.
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