ArticleRheumatology international2015
The clinical burden of generalized osteoarthritis represented by self-reported health-related quality of life and activity limitations: a cross-sectional study.
Article in Rheumatology international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Defining multiple joint osteoarthritis, its frequency and impact in a community-based cohort.Seminars in arthritis and rheumatism · 2019Pooled it
- A systematic review assessing non-pharmacological conservative treatment studies for people with non-inflammatory multi-joint pain: clinical outcomes and research design considerations.Rheumatology international · 2018Pooled it
- Ultrasound findings in patients with knee osteoarthritis: Relationships with clinical characteristics, radiographic findings and generalized osteoarthritis.Osteoarthritis and cartilage open · 2025Article
- Impact of 3 Months of Supervised Exercise on Function by Arthritis Status.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025Article
- The Extent and Nature of Functional Limitations According to the Health Assessment Questionnaire Disability Index in Patients with Rheumatoid Arthritis and Severe Functional Disability.Journal of clinical medicine · 2024Article
- Osteoarthritis and Diabetes: Where Are We and Where Should We Go?Diagnostics (Basel, Switzerland) · 2023Review
- Prevalence of activity limitation and its associated predictor among the elderly in Tamil Nadu, India: A community-based cross-sectional study.Journal of education and health promotion · 2023Article
- The contribution of age and obesity to the number of painful joint sites in individuals reporting osteoarthritis: a population-based study.Rheumatology (Oxford, England) · 2020Article
- The prevalence of type 2 diabetes and associated risk factors with generalized osteoarthritis: a retrospective study using ICD codes for clinical data repository system.Clinical rheumatology · 2019Article
- Joint hypermobility is not positively associated with prevalent multiple joint osteoarthritis: a cross-sectional study of older adults.BMC musculoskeletal disorders · 2019Article
- WHO disability assessment schedule 2.0 is related to upper and lower extremity disease-specific quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018Article
- Patient-reported outcome measures in osteoarthritis: a systematic search and review of their use and psychometric properties.RMD open · 2018Article
- Distribution of osteoarthritis in a Norwegian population-based cohort: associations to risk factor profiles and health-related quality of life.Rheumatology international · 2017Article
- Health and Lifestyles Factors Associated With Osteoarthritis among Older Adults in Portugal.Frontiers in medicine · 2017Article
- Article
- The clinical characteristics of older people with chronic multiple-site joint pains and their utilisation of therapeutic interventions: data from a prospective cohort study.BMC musculoskeletal disorders · 2016Observational
- Evaluation of quality of life in chronic, progressing rheumatic diseases based on the example of osteoarthritis and rheumatoid arthritis.Clinical interventions in aging · 2016Article
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Authors and funding
6 authors.
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Abstract
The involvement of multiple joints is common in osteoarthritis (OA), often referred to as generalized osteoarthritis (GOA). However, since research and practice mainly focus on a specific OA localization, the health status of patients with GOA is largely unknown. Therefore, we aimed to describe the clinical burden of GOA in terms of self-reported health-related quality of life (HRQoL) and activity limitations. In this cross-sectional study, individuals clinically diagnosed with GOA and referred to multidisciplinary treatment, completed questionnaires on socio-demographics, joint involvement, HRQoL (SF-36) and activity limitations (HAQ-DI). SF-36 physical (PCS) and mental component summary scores (MCS) were calculated using norm-based data. The patient's specific most important activity limitations were linked to the International Classification of Functioning, Disability and Health. A total of 147 patients participated [85 % female; mean (SD) age 60 (8) years]. The majority (93 %) had symptomatic OA in both the upper and lower extremities. Predominant joints with symptomatic OA were the hands (85 %) and knees (82 %). Mean (SD) SF-36 PCS and MCS scores were 37 (7) and 48 (10), respectively, showing a broad impact of GOA on the physical component of health. The mean (SD) HAQ-DI score was 1.27 (0.50) indicating moderate to severe functional limitations. Activities concerning mobility and domestic life were considered most important activity limitations, especially walking. The results show a high clinical burden of GOA in terms of HRQoL and activity limitations. This study points to the need of developing non-pharmacological interventions for patients with GOA that should target on improving the physical component of health and mobility limitations.
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