Evidence map›Paper›PMID 25300335›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

Role of Appropriate Therapy in Combating Mortality among the Ventilated Patients.

M V Pravin Charles, Joshy M Easow, Noyal M Joseph, M Ravishankar, Shailesh Kumar, Sivaraman Umadevi

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In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Ventilator-Associated Pneumonia: The Role of Emerging Diagnostic Technologies.Seminars in respiratory and critical care medicine · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M V Pravin CharlesAssistant Professor, Department of Microbiology, Mahatma Gandhi Medical College and Research Institute , Pondicherry, India .
Joshy M EasowProfessor, Department of Microbiology, Mahatma Gandhi Medical College and Research Institute , Pondicherry, India .
Noyal M JosephAssistant Professor, Department of Microbiology, Mahatma Gandhi Medical College and Research Institute , Pondicherry, India .
M RavishankarProfessor Department of Anesthesiology and Critical Care, Mahatma Gandhi Medical College and Research Institute , Pondicherry, India .
Shailesh KumarProfessor, Department of Microbiology, Mahatma Gandhi Medical College and Research Institute , Pondicherry, India .
Sivaraman UmadeviProfessor, Department of Microbiology, Mahatma Gandhi Medical College and Research Institute , Pondicherry, India .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextVentilator associated pneumonia (VAP) is a nosocomial infection prevalent among the intensive care unit (ICU) patients despite proper infection control practices. The diagnosis of VAP still remains controversial and hence the mortality rate is higher among this group of patients.

aimThe aim of our study was to identify the antibiotic pattern and the appropriateness of treatment followed in the ICU in relation with the clinical pulmonary infection score (CPIS) as a tool to diagnose VAP. This was compared with patients who had an inappropriate treatment in comparison to the CPIS and the clinical outcome.

resultsOut of the 18 VAP patients, 12 (66.7%) received appropriate therapy based on the antibiotic susceptibility pattern of the causative organism, while 1 (5.5%) received partially inappropriate therapy and 5 (27.8%) received totally inappropriate therapy. Nine of the 18 (50%) VAP patients died, while only 5 of the 58 (8.6%) patients without VAP died. 72.2% patients with VAP received appropriate treatment based on the sensitivity of the isolates. The mortality rate in VAP patients receiving inappropriate therapy was 80%, while in those receiving appropriate therapy the mortality rate was 38.5%. The mortality rate among VAP patients with blood culture positivity was 100%, while it was 43.75% among those with negative blood culture.

conclusionThe mortality rate among the patients receiving inappropriate therapy is high compared to other group of patients. Hence, a proper evaluation and administration of appropriate antibiotics can curb mortality among the ventilated patients.

Indexed as

APACHE (acute physiology and chronic health evaluation) II scoresClinical pulmonary infection scoreEndotracheal aspirateVentilator associated pneumonia

Identifiers

PMID25300335
PMCPMC4190713

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.