Evidence map›Paper›PMID 25299687›Full record

ArticlePloS one2014

Full genome characterization of the culicoides-borne marsupial orbiviruses: Wallal virus, Mudjinbarry virus and Warrego viruses.

Manjunatha N Belaganahalli, Sushila Maan, Narender S Maan, Ian Pritchard, Peter D Kirkland, Joe Brownlie, Houssam Attoui, Peter P C Mertens

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Tick-borne piroplasms and trypanosomes incidentally detected in eastern grey kangaroos (International journal for parasitology. Parasites and wildlife · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Manjunatha N BelaganahalliVector-borne Viral Diseases Programme, Institute for Animal Health, Pirbright, Woking, Surrey, United Kingdom.
Sushila MaanVector-borne Viral Diseases Programme, Institute for Animal Health, Pirbright, Woking, Surrey, United Kingdom.
Narender S MaanVector-borne Viral Diseases Programme, Institute for Animal Health, Pirbright, Woking, Surrey, United Kingdom.
Ian PritchardAustralian Animal Health Laboratory, CSIRO, Geelong, Victoria, Australia.
Peter D KirklandElizabeth Macarthur Agricultural Institute, Camden, New South Wales, Australia.
Joe BrownlieDepartment of Pathology and Infectious Diseases, Royal Veterinary College, North Mymms, Hatfield, Herts, United Kingdom.
Houssam AttouiVector-borne Viral Diseases Programme, Institute for Animal Health, Pirbright, Woking, Surrey, United Kingdom.
Peter P C MertensVector-borne Viral Diseases Programme, Institute for Animal Health, Pirbright, Woking, Surrey, United Kingdom.
The Pirbright Institute · GBAustralian Centre for Disease Preparedness · AUNew South Wales Department of Primary Industries · AURoyal Veterinary College · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00001144Biotechnology and Biological Sciences Research Council BBS/E/I/00001446
6 · The paper itself

Abstract

Viruses belonging to the species Wallal virus and Warrego virus of the genus Orbivirus were identified as causative agents of blindness in marsupials in Australia during 1994/5. Recent comparisons of nucleotide (nt) and amino acid (aa) sequences have provided a basis for the grouping and classification of orbivirus isolates. However, full-genome sequence data are not available for representatives of all Orbivirus species. We report full-genome sequence data for three additional orbiviruses: Wallal virus (WALV); Mudjinabarry virus (MUDV) and Warrego virus (WARV). Comparisons of conserved polymerase (Pol), sub-core-shell 'T2' and core-surface 'T13' proteins show that these viruses group with other Culicoides borne orbiviruses, clustering with Eubenangee virus (EUBV), another orbivirus infecting marsupials. WARV shares <70% aa identity in all three conserved proteins (Pol, T2 and T13) with other orbiviruses, consistent with its classification within a distinct Orbivirus species. Although WALV and MUDV share <72.86%/67.93% aa/nt identity with other orbiviruses in Pol, T2 and T13, they share >99%/90% aa/nt identities with each other (consistent with membership of the same virus species - Wallal virus). However, WALV and MUDV share <68% aa identity in their larger outer capsid protein VP2(OC1), consistent with membership of different serotypes within the species - WALV-1 and WALV-2 respectively.

Indexed as

Amino Acid SequenceAnimalsBase SequenceCeratopogonidaeGenome, ViralMarsupialiaMolecular Sequence DataOrbivirusPhylogenySequence AnalysisViral Structural ProteinsViral Structural Proteins

Identifiers

PMID25299687
PMCPMC4191977
OpenAlexW1999570313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.