Evidence map›Paper›PMID 25298964›Full record

ReviewBioMed research international2014

Combating pathogenic microorganisms using plant-derived antimicrobials: a minireview of the mechanistic basis.

Abhinav Upadhyay, Indu Upadhyaya, Anup Kollanoor-Johny, Kumar Venkitanarayanan

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
20.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 219 citations in OpenAlex.

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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Abhinav UpadhyayDepartment of Animal Science, University of Connecticut, 3636 Horsebarn Hill Road Extension, Unit 4040, Storrs, CT 06269, USA.ORCID 0000-0002-6064-4858
Indu UpadhyayaDepartment of Animal Science, University of Connecticut, 3636 Horsebarn Hill Road Extension, Unit 4040, Storrs, CT 06269, USA.
Anup Kollanoor-JohnyDepartment of Animal Science, University of Connecticut, 3636 Horsebarn Hill Road Extension, Unit 4040, Storrs, CT 06269, USA.
Kumar VenkitanarayananDepartment of Animal Science, University of Connecticut, 3636 Horsebarn Hill Road Extension, Unit 4040, Storrs, CT 06269, USA.ORCID 0000-0001-5966-7852
University of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of antibiotic resistance in pathogenic bacteria has led to renewed interest in exploring the potential of plant-derived antimicrobials (PDAs) as an alternative therapeutic strategy to combat microbial infections. Historically, plant extracts have been used as a safe, effective, and natural remedy for ailments and diseases in traditional medicine. Extensive research in the last two decades has identified a plethora of PDAs with a wide spectrum of activity against a variety of fungal and bacterial pathogens causing infections in humans and animals. Active components of many plant extracts have been characterized and are commercially available; however, research delineating the mechanistic basis of their antimicrobial action is scanty. This review highlights the potential of various plant-derived compounds to control pathogenic bacteria, especially the diverse effects exerted by plant compounds on various virulence factors that are critical for pathogenicity inside the host. In addition, the potential effect of PDAs on gut microbiota is discussed.

Indexed as

AnimalsAnti-Infective AgentsBacteriaFungiHumansParasitesPlantsAnti-Infective Agents

Identifiers

PMID25298964
PMCPMC4178913
OpenAlexW2085556012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.