ArticleEndocrinology, diabetes & metabolism case reports2014
Effect of Astragalus membranaceus extract on diabetic nephropathy.
Article in Endocrinology, diabetes & metabolism case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
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- Unlocking the mechanistic potential ofJournal of traditional and complementary medicine · 2024Review
- Medicinal Herbs: Promising Immunomodulators for the Treatment of Infectious Diseases.Molecules (Basel, Switzerland) · 2023Review
- Anti-obesity and Gut Microbiota Modulation Effect of Astragalus Polysaccharides Combined with Berberine on High-Fat Diet-Fed Obese Mice.Chinese journal of integrative medicine · 2023Article
- Molecular Mechanistic Pathways Targeted by Natural Antioxidants in the Prevention and Treatment of Chronic Kidney Disease.Antioxidants (Basel, Switzerland) · 2021Review
- Protective Effect of Keluoxin against Diabetic Nephropathy in Type 2 Diabetic Mellitus Models.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Astragaloside IV alleviates mouse slow transit constipation by modulating gut microbiota profile and promoting butyric acid generation.Journal of cellular and molecular medicine · 2020Article
- Effect ofBioMed research international · 2020Article
- Astragalus membranaceus and Punica granatum alleviate infertility and kidney dysfunction induced by aging in male rats.Turkish journal of biology = Turk biyoloji dergisi · 2020Article
- Jixuepaidu Tang-1 inhibits epithelial-mesenchymal transition and alleviates renal damage in DN mice through suppressing long non-coding RNA LOC498759.Cell cycle (Georgetown, Tex.) · 2019Article
- Identification and Isolation of Active Compounds fromBiomolecules · 2019Article
- Article
- Herbal acupuncture for type 2 diabetes: A meta-analysis.Experimental and therapeutic medicine · 2017Article
- Effect of astragalus injection on renal tubular epithelial transdifferentiation in type 2 diabetic mice.BMC complementary and alternative medicine · 2016Article
- Natural Products to Counteract the Epidemic of Cardiovascular and Metabolic Disorders.Molecules (Basel, Switzerland) · 2016Review
- Effects of Astragalus polysaccharides on memory impairment in a diabetic rat model.Neuropsychiatric disease and treatment · 2016Article
- Shen-Kang protects 5/6 nephrectomized rats against renal injury by reducing oxidative stress through the MAPK signaling pathways.International journal of molecular medicine · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledDiabetic nephropathy, a microvascular complication of diabetes, is a progressive kidney disease caused by angiopathy of the capillaries in the kidney glomeruli. Herein, we report a case of a 62-year-old patient with a 30 year history of diabetes, who showed a substantial improvement in diabetic nephropathy on administration of 30 g of Astragalus membranaceus extract per day. After 1 month, estimated glomerular filtration rate increased from 47 to 72 ml/min per 1.73 m(2) and was subsequently maintained at the 1-month follow-up. Urinary protein levels also decreased following treatment. Herein, we present and discuss the evidence and mechanism of A. membranaceus on diabetic nephropathy in this patient. LEARNING POINTS: Diabetic nephropathy is a progressive kidney disease.Angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) are currently used to prevent and delay the progression of diabetic nephropathy. However, their effects are not sufficient to prevent a decline in kidney function.Furthermore, combination therapy with an ACE inhibitor and an ARB can produce adverse effects without additional benefits.In the early phase of diabetic nephropathy, administration of Astragalus membranaceus can be a therapeutic option.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.