Evidence map›Paper›PMID 25298858›Full record

ArticleJournal of vascular and interventional neurology2014

Enrollment of research subjects through telemedicine networks in a multicenter acute intracerebral hemorrhage clinical trial: design and methods.

J Alfredo Caceres, David M Greer, Joshua N Goldstein, Anand Viswanathan, Jose I Suarez, Logan Brau, Joseph Christopher Zacko, Theodore J Lowenkopf, Chad M Miller, Qaisar A Shah and 5 more

Abstract read
In one paragraph

Article in Journal of vascular and interventional neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Telemedicine Provides Noninferior Research Informed Consent for Remote Study Enrollment: A Randomized Controlled Trial.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2016
    Trial
  2. Article
  3. Article
  4. Article
  5. Interventions to improve access to clinical trials in urologic oncology.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

J Alfredo CaceresZeenat Qureshi Stroke Institute, St Cloud MN, USA.
David M GreerYale University School of Medicine, Department of Neurology, New Haven, CT, USA.
Joshua N GoldsteinHarvard Medical School, Center for Neurologic Emergencies, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA.
Anand ViswanathanHarvard Medical School, Telestroke Services, Massachusetts General Hospital, Boston, MA, USA.
Jose I SuarezSection of Vascular Neurology and Neurocritical Care, Baylor College of Medicine, Houston, TX, USA.
Logan BrauZeenat Qureshi Stroke Institute, St Cloud MN, USA.
Joseph Christopher ZackoPenn State Hershey Neurosurgery, Hershey, PA, USA.
Theodore J LowenkopfOregon Health and Science University, Department of Neurology, Providence Stroke Center, Portland, OR, USA.
Chad M MillerWexner Medical Center, The Ohio State University, Columbus, OH, USA.
Qaisar A ShahNeurointerventional and Neurocritical Care Services, Neurosciences Institute, Abington Memorial Hospital, Abington, PA, USA.
Ira ChangAcute Neurological Services, Swedish Medical Center, Englewood, CO, USA.
Souvik SenDepartment of Neurology, University of South Carolina School of Medicine, Columbia, SC, USA.
Steven R MesseHospital of the University of Pennsylvania, Philadelphia, PA, USA.
Sherry H ChouHarvard Medical School, Boston, MA, USA.
Adnan I QureshiZeenat Qureshi Stroke Institute, St Cloud MN, USA ; Zeenat Qureshi Stroke Institute, St Cloud, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnrollment of subjects in acute stroke trials is often hindered by narrow timeframes, because a large proportion of patients arrive via transfers from outside facilities rather than primary arrival at the enrolling hospital. RATIONALE: Telemedicine networks have been increasingly used for provision of care for acute stroke patients at facilities outside of major academic centers. Treatment decisions made through telemedicine networks in patients with acute ischemic stroke have been shown to be safe, reliable, and effective. With the expanding use of this technology and the impediments to enrolling subjects into clinical trials, this approach can be applied successfully to the field of clinical research. METHODS AND

conclusionsThe Antihypertensive Treatment of Acute Cerebral Hemorrhage II trial is a phase III randomized multicenter trial that has developed a protocol in collaboration with participating sites to implement the use of telemedicine networks for the enrollment of research subjects. The protocol describes the operating procedures and legal and Institutional Review Board perspectives for its implementation.

Identifiers

PMID25298858
PMCPMC4188255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.