ArticleIndian journal of clinical biochemistry : IJCB2014
Maternal leptin, adiponectin, resistin, visfatin and tumor necrosis factor-alpha in normal and gestational diabetes.
Article in Indian journal of clinical biochemistry : IJCB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Lymphocyte Subsets and Cytokine Changes in Women With Gestational Diabetes Mellitus: A Systematic Review.Journal of diabetes research · 2025Pooled it
- Serum levels of adipokines in gestational diabetes: a systematic review.Journal of endocrinological investigation · 2019Pooled it
- Interventional effect of dietary fiber on blood glucose and pregnancy outcomes in patients with gestational diabetes mellitus.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2021Trial
- Efficiency of afamin and fibroblast growth factor 21 for early prediction of gestational diabetes mellitus.Scientific reports · 2026Article
- First-trimester adipocytokine levels as predictive biomarkers for preeclampsia: a prospective case-control study.European journal of medical research · 2026Article
- Serum resistin increases in gestational diabetes but does not differ among various trimesters.Heliyon · 2025Article
- Endostatin and Cystatin C as Potential Biomarkers for Early Prediction of Preeclampsia.ACS omega · 2023Article
- Article
- Association between serum interleukin-6, leptin and insulin in gestational diabetes mellitus - a cross- sectional study.Journal of diabetes and metabolic disorders · 2023Article
- Influence of Pre-Pregnancy Obesity on Carbohydrate and Lipid Metabolism with Selected Adipokines in the Maternal and Fetal Compartment.Nutrients · 2023Article
- Dietary Blueberry and Soluble Fiber Improve Serum Antioxidant and Adipokine Biomarkers and Lipid Peroxidation in Pregnant Women with Obesity and at Risk for Gestational Diabetes.Antioxidants (Basel, Switzerland) · 2021Article
- Resistin in pregnancy: Analysis of determinants in pairs of umbilical cord blood and maternal serum.Cytokine: X · 2021Article
- Article
- Maternal serum level of resistin is associated with risk for gestational diabetes mellitus: A meta-analysis.World journal of clinical cases · 2019Article
- First-trimester multimarker prediction of gestational diabetes mellitus using targeted mass spectrometry.Diabetologia · 2016Article
- The levels of human milk microRNAs and their association with maternal weight characteristics.European journal of clinical nutrition · 2016Article
- Relationships between plasma leptin levels, leptin G2548A, leptin receptor Gln223Arg polymorphisms and gestational diabetes mellitus in Chinese population.Scientific reports · 2016Article
- Impact of Systemic Inflammation on the Progression of Gestational Diabetes Mellitus.Current diabetes reports · 2016Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gestational diabetes mellitus (GDM) is a common medical complication associated with pregnancy. The present study evaluates the changes in maternal adipocytokines (leptin, adiponectin, resistin, visfatin and tumor necrosis factor-alpha; TNF-α) in pregnancy complicated with GDM compared to normal pregnancy at 2nd and 3rd trimesters. The study included total number of 142 pregnant women classified into 4 groups: normal pregnancy (n = 33) and pregnancy with GDM (n = 24) both at 2nd trimester and normal pregnancy (n = 38) and GDM (n = 47) at 3rd trimester. Both GDM groups were significantly presented with elevated body mass index, fasting blood sugar and abnormal oral glucose tolerance test compared to their matched control. Results indicated reduction in maternal serum leptin and adiponectin in GDM compared to normal pregnancy at 3rd trimester. Elevated resistin and TNF-α were evident among pregnancy complicated with GDM at both tested trimesters. On the other hand, significant elevation in maternal visfatin was noted between GDM and matched control at 2nd trimester only. Significant increase in maternal leptin and visfatin and resistin was noted by advances in gestational period in healthy pregnancy. On the other hand, reduced adiponectin and elevated visfatin mean values were noticed in GDM at 3rd compared to 2nd trimester. It could be concluded that increased insulin resistance accompanies GDM is associated with suppressed leptin and adiponectin and increased resistin and TNF-α which might suggest their involvement in the development of GDM.
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Registered trials
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