Evidence map›Paper›PMID 25297327›Full record

ArticleJournal of clinical microbiology2014

A highly sensitive europium nanoparticle-based immunoassay for detection of influenza A/B virus antigen in clinical specimens.

Panhe Zhang, Sai Vikram Vemula, Jiangqin Zhao, Bingchen Du, Haleyurgirisetty Mohan, Jikun Liu, Haja Sittana El Mubarak, Marie L Landry, Indira Hewlett

Open access · bronzeAbstract readComparative StudyEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Panhe ZhangLaboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA.
Sai Vikram VemulaLaboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA saivikram.vemula@fda.hhs.gov indira.hewlett@fda.hhs.gov.
Jiangqin ZhaoLaboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA.
Bingchen DuLaboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA.
Haleyurgirisetty MohanLaboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA.
Jikun LiuLaboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA.
Haja Sittana El MubarakCenter for Devices and Radiological Health, Food and Drug Administration, Silver Spring, Maryland, USA.
Marie L LandryDepartment of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Indira HewlettLaboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA saivikram.vemula@fda.hhs.gov indira.hewlett@fda.hhs.gov.
Center for Biologics Evaluation and Research · USCenter for Devices and Radiological Health · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the development of a novel europium nanoparticle-based immunoassay (ENIA) for rapid detection of influenza A and influenza B viruses. The ENIA demonstrated sensitivities of 90.7% (147/162) for influenza A viruses and 81.80% (9/11) for influenza B viruses compared to those for an in-house reverse transcription (RT)-PCR assay in testing of influenza-positive clinical samples.

Indexed as

EuropiumNanoparticlesAntigens, ViralDiagnostic Tests, RoutineHumansImmunoassayInfluenza A virusInfluenza B virusInfluenza, HumanSensitivity and SpecificityAntigens, ViralEuropium

Identifiers

PMID25297327
PMCPMC4313323
OpenAlexW2120879520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.