ArticleNature communications2014
Conformational transitions and stop-and-go nanopore transport of single-stranded DNA on charged graphene.
Article in Nature communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed.
- Diffusion of DNA on Atomically Flat 2D Material Surfaces.ACS nano · 2025Article
- Exploring 2D Graphene-Based Nanomaterials for Biomedical Applications: A Theoretical Modeling Perspective.Small science · 2025Article
- Interplay of graphene-DNA interactions: Unveiling sensing potential of graphene materials.Applied physics reviews · 2024Article
- Effect of surface functionalization on DNA sequencing using MXene-based nanopores.RSC advances · 2024Article
- Versatile carbon nanoplatforms for cancer treatment and diagnosis: strategies, applications and future perspectives.Theranostics · 2022Review
- Effect of Shape on the Entering of Graphene Quantum Dots into a Membrane: A Molecular Dynamics Simulation.ACS omega · 2021Article
- Translocation of DNA through Ultrathin Nanoslits.Advanced materials (Deerfield Beach, Fla.) · 2021Article
- Vibrational Spectra of Nucleotides in the Presence of the Au Cluster Enhancer in MD Simulation of a SERS Sensor.Biosensors · 2021Article
- High-Fidelity Capture, Threading, and Infinite-Depth Sequencing of Single DNA Molecules with a Double-Nanopore System.ACS nano · 2020Article
- Roles of entropic and solvent damping forces in the dynamics of polymer tethered nanoparticles and implications for single molecule sensing.Chemical science · 2020Article
- Efficient miRNA Inhibitor Delivery with Graphene Oxide-Polyethylenimine to Inhibit Oral Squamous Cell Carcinoma.International journal of nanomedicine · 2020Article
- Fabrication and Applications of Solid-State Nanopores.Sensors (Basel, Switzerland) · 2019Review
- Article
- Modulation of Molecular Flux Using a Graphene Nanopore Capacitor.The journal of physical chemistry. B · 2017Article
- Conformation Change, Tension Propagation and Drift-Diffusion Properties of Polyelectrolyte in Nanopore Translocation.Polymers · 2016Article
- Graphene Nanopores for Protein Sequencing.Advanced functional materials · 2016Article
- Molecular Dynamics Simulation of DNA Capture and Transport in Heated Nanopores.ACS applied materials & interfaces · 2016Article
- Origin of the Shape of Current-Voltage Curve through Nanopores: A Molecular Dynamics Study.Scientific reports · 2016Article
- Article
- Polyelectrolyte Threading through a Nanopore.Polymers · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Control over interactions with biomolecules holds the key to applications of graphene in biotechnology. One such application is nanopore sequencing, where a DNA molecule is electrophoretically driven through a graphene nanopore. Here we investigate how interactions of single-stranded DNA and a graphene membrane can be controlled by electrically biasing the membrane. The results of our molecular dynamics simulations suggest that electric charge on graphene can force a DNA homopolymer to adopt a range of strikingly different conformations. The conformational response is sensitive to even very subtle nucleotide modifications, such as DNA methylation. The speed of DNA motion through a graphene nanopore is strongly affected by the graphene charge: a positive charge accelerates the motion, whereas a negative charge arrests it. As a possible application of the effect, we demonstrate stop-and-go transport of DNA controlled by the charge of graphene. Such on-demand transport of DNA is essential for realizing nanopore sequencing.
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Registered trials
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