Evidence map›Paper›PMID 25296353›Full record

ReviewBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2014

Chronic granulomatous disease: why an inflammatory disease?

P Roxo-Junior, H M L Simão

Abstract readReview
In one paragraph

Review in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Chronic Granulomatous Disease.Journal of clinical and diagnostic research : JCDR · 2015
    Article
  9. Ulcerative colitis associated with chronic granulomatous disease: case report.Gastroenterology and hepatology from bed to bench · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

P Roxo-JuniorDepartamento de Pediatria, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil.
H M L SimãoDepartamento de Biologia e Farmácia, Faculdade de Medicina de Santa Cruz, Universidade de Santa Cruz do Sul, Santa Cruz do Sul, RS, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic granulomatous disease is a primary immunodeficiency caused by mutations in the genes encoding subunits of the phagocytic NADPH oxidase system. Patients can present with severe, recurrent infections and noninfectious conditions. Among the latter, inflammatory manifestations are predominant, especially granulomas and colitis. In this article, we systematically review the possible mechanisms of hyperinflammation in this rare primary immunodeficiency condition and their correlations with clinical aspects.

Indexed as

Granulomatous Disease, ChronicHumansInflammation MediatorsNADPH OxidasesNeutrophilsReactive Oxygen SpeciesInflammation MediatorsNADPH OxidasesReactive Oxygen Species

Identifiers

PMID25296353
PMCPMC4230281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.