Evidence map›Paper›PMID 25295826›Full record

ReviewRevista Brasileira de terapia intensiva

Prognostic value of circulating DNA levels in critically ill and trauma patients.

Edison Moraes Rodrigues Filho, Nilo Ikuta, Daniel Simon, Andrea Pereira Regner

Registry-linked trialOpen access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Revista Brasileira de terapia intensiva. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03539497 (Prognostic Value of Plasma Mitochondrial DNA and Cytochrome C After Cardiac Arrest), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03539497 unknown statusnot on this map

Prognostic Value of Plasma Mitochondrial DNA and Cytochrome C After Cardiac Arrest

TypeobservationalSponsorUniversity Medical Centre LjubljanaRan2019 to 2024Enrolled87ConditionsCardiac ArrestArmsBiomarker
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Edison Moraes Rodrigues FilhoLaboratório de Biomarcadores do Trauma, Universidade Luterana do Brasil, Canoas, RS, Brasil.
Nilo IkutaLaboratório de Biomarcadores do Trauma, Universidade Luterana do Brasil, Canoas, RS, Brasil.
Daniel SimonLaboratório de Biomarcadores do Trauma, Universidade Luterana do Brasil, Canoas, RS, Brasil.
Andrea Pereira RegnerLaboratório de Biomarcadores do Trauma, Universidade Luterana do Brasil, Canoas, RS, Brasil.
Universidade Luterana do Brasil · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number of studies investigating circulating nucleic acids as potential biomarkers has increased in recent years. The detection of such biomarkers is a minimally invasive alternative for the diagnosis and prognosis of various clinical conditions. The value of circulating DNA levels as a predictive biomarker has been demonstrated in patients suffering from numerous acute pathologies that have a high risk of intensive care needs and in-hospital deaths. The mechanism by which circulating DNA levels increase in patients with these conditions remains unclear. In this review, we focused on the potential use of this biomarker for prognosis prediction in critically ill and trauma patients. The literature review was performed by searching MedLine using PubMed in the English language.

Indexed as

Critical IllnessBiomarkersCritical CareDNAHumansPrognosisWounds and InjuriesBiomarkersDNA

Identifiers

PMID25295826
PMCPMC4188468
OpenAlexW2131642599

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.