ArticleThe American journal of managed care2014
The effect of depression treatment on work productivity.
Article in The American journal of managed care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Towards a better understanding of work participation among employees with common mental health problems: a systematic realist review.Scandinavian journal of work, environment & health · 2022Pooled it
- Nocturia Work Productivity and Activity Impairment Compared with Other Common Chronic Diseases.PharmacoEconomics · 2016Pooled it
- Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 1. Disease Burden and Principles of Care.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2016Pooled it
- Categorical improvement in functional impairment in depressed patients treated with desvenlafaxine.CNS spectrums · 2019Trial
- Enhancing Depression Identification and Stratification with a Claims-Based Analytical Framework.The journal of behavioral health services & research · 2026Article
- Article
- Factors associated with return to work among disability claimants with depression.African journal of disability · 2025Article
- Diet and Depression during Peri- and Post-Menopause: A Scoping Review Protocol.Methods and protocols · 2023Article
- Gathering the Evidence on Diet and Depression: A Protocol for an Umbrella Review and Updated Meta-Analyses.Methods and protocols · 2023Article
- Association of burnout with depression in pharmacists: A network analysis.Frontiers in psychiatry · 2023Article
- Depression, anxiety and stress among people infected with COVID-19 in Dhaka and Chittagong cities.Heliyon · 2022Article
- Humanistic and economic burden associated with depression in the United States: a cross-sectional survey analysis.BMC psychiatry · 2022Article
- Exploring the Role of Nutraceuticals in Major Depressive Disorder (MDD): Rationale, State of the Art and Future Prospects.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Mental Health and Psychosocial Functioning in Recently Separated U.S. Women Veterans: Trajectories and Bi-Directional Relationships.International journal of environmental research and public health · 2021Article
- An Ecological Study of a Universal Employee Depression Awareness and Stigma Reduction Intervention: "Right Direction".Frontiers in psychiatry · 2021Article
- Working Conditions in Social Firms and Health Promotion Interventions in Relation to Employees' Health and Work-Related Outcomes-A Scoping Review.International journal of environmental research and public health · 2020Article
- Reducing Workplace Absenteeism Caused by Work Stress in a Health Maintenance Organization Department of Psychiatry.The Permanente journal · 2020Article
- Impact of Cognitive Symptoms on Health-Related Quality of Life and Work Productivity in Chinese Patients with Major Depressive Disorder: Results from the PROACT Study.Neuropsychiatric disease and treatment · 2020Article
- The humanistic and economic burden of treatment-resistant depression in Europe: a cross-sectional study.BMC psychiatry · 2019Observational
- Trajectories of antidepressant medication use in individuals before and after being granted disability pension due to common mental disorders- a nationwide register-based study.BMC psychiatry · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectivesDepression is associated with lowered work functioning, including absence, productivity impairment at work, and decreased job retention. Although high-quality depression treatment provided in clinical trials has been found to reduce symptoms and improve work function, the effectiveness of routine treatment for depression in primary care has received less attention. STUDY
designThis prospective cohort study investigated the relationship between improvements in both depression symptoms and productivity in outpatients from 77 clinics in Minnesota following routine depression treatment.
methodsData were obtained from patients receiving usual care for depression prior to initiation of a statewide quality improvement collaborative called DIAMOND (Depression Improvement Across Minnesota: Offering a New Direction). Patients started on antidepressants were surveyed on depression symptom severity (Patient Health Questionnaire [PHQ-9]), productivity loss (Work Productivity and Activity Impairment questionnaire [WPAI]), health status, and demographics. Data were collected again 6 months later to assess changes in depression symptoms and productivity.
resultsData from 432 employed patients with complete baseline and outcome data showed significant reductions in depression symptoms and increases in productivity (P < .0001) over 6 months. Greater improvements in productivity at 6 months were associated with greater improvement in depression symptoms as well as with greater depression severity (P < .0001) and poorer productivity (P < .0001) at baseline.
conclusionsThis study demonstrated a significant relationship betweenimprovement in depression symptoms and improvements in productivity following routine primary care depression treatment. These findings underscore the benefit of depression care to improve work outcomes and to yield a potential return on healthcare investment to employers.
Indexed as
Identifiers
25295792PMC4214368W2417860654What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.