Evidence map›Paper›PMID 25295272›Full record

ReviewBioMed research international2014

Curcumin: a potential candidate in prevention of cancer via modulation of molecular pathways.

Arshad H Rahmani, Mohammad A Al Zohairy, Salah M Aly, Masood A Khan

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 183 citations in OpenAlex.

  1. Review
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  8. A Review of the Role of Curcumin in Metal Induced Toxicity.Antioxidants (Basel, Switzerland) · 2023
    Review
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  11. Article
  12. Article
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  16. Review
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  19. Targeting key transcriptional factor STAT3 in colorectal cancer.Molecular and cellular biochemistry · 2021
    Review
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Arshad H RahmaniDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraida, Saudi Arabia.
Mohammad A Al ZohairyDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraida, Saudi Arabia.
Salah M AlyDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraida, Saudi Arabia ; Department of Pathology, Faculty of Vet. Medicine, Suez Canal University, Ismailia, Egypt.
Masood A KhanDepartment of Basic Health Science, College of Applied Medical Sciences, Qassim University, Saudi Arabia.
Qassim University · SASuez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is the most dreadful disease worldwide in terms of morbidity and mortality. The exact cause of cancer development and progression is not fully known. But it is thought that cancer occurs due to the structural and functional changes in the genes. The current approach to cancer treatment based on allopathic is expensive, exhibits side effects; and may also alter the normal functioning of genes. Thus, a safe and effective mode of treatment is needed to control the cancer development and progression. Some medicinal plants provide a safe, effective and affordable remedy to control the progression of malignant cells. The importance of medicinal plants and their constituents has been documented in Ayurveda, Unani medicine, and various religious books. Curcumin, a vital constituent of the spice turmeric, is an alternative approach in the prevention of cancer. Earlier studies have shown the effect of curcumin as an antioxidant, antibacterial, antitumor and it also has a noteworthy role in the control of different diseases. In this review, we summarize the understanding of chemopreventive effects of curcumin in the prevention of cancer via the regulation of various cell signaling and genetic pathways.

Indexed as

Plants, MedicinalAntioxidantsCurcumaCurcuminGene Expression Regulation, NeoplasticHumansMedicine, AyurvedicNeoplasmsSignal TransductionAntioxidantsCurcumin

Identifiers

PMID25295272
PMCPMC4176907
OpenAlexW2116046043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.