Evidence map›Paper›PMID 25295192›Full record

ArticleJournal of aging research2014

Could some geriatric characteristics hinder the prescription of anticoagulants in atrial fibrillation in the elderly?

Paule Denoël, Jacques Vanderstraeten, Pierre Mols, Thierry Pepersack

Open access · goldAbstract read
In one paragraph

Article in Journal of aging research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Characteristics of warfarin under-prescription in older adults with atrial fibrillation.International journal of cardiology. Heart & vasculature · 2021
    Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Paule DenoëlEmergency Service, Europe Hospital, 1040 Brussels, Belgium.ORCID 0000-0003-0735-4664
Jacques VanderstraetenCentre de Recherche en Santé Environnementale et en Santé du Travail, Ecole de Santé Publique, Université Libre de Bruxelles, 1070 Brussels, Belgium.
Pierre MolsEmergency Service, Saint-Pierre University Hospital, Université Libre de Bruxelles, 1000 Brussels, Belgium.ORCID 0000-0001-8320-1171
Thierry PepersackDepartment of Geriatrics, Erasme Hospital, Université Libre de Bruxelles, Lennik Street 808, 1070 Brussels, Belgium.ORCID 0000-0001-6197-582X
Université Libre de Bruxelles · BEEurope Hospitals · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have reported underprescription of anticoagulants in atrial fibrillation (AF). We conducted an observational study on 142 out of a total of 995 consecutive ≥75 years old patients presenting AF (14%) when admitted in an emergency unit of a general hospital, in search of geriatric characteristics that might be associated with the underprescription of anticoagulation therapy (mostly antivitamin K at the time of the study). The following data was collected from patients presenting AF: medical history including treatment and comorbidities, CHADS2 score, ISAR scale (frailty), Lawton's scale (ADL), GDS scale (mood status), MUST (nutrition), and blood analysis (INR, kidney function, and albumin). Among those patients for who anticoagulation treatment was recommended (73%), only 61% were treated with it. In the group with anticoagulation therapy, the following characteristics were observed more often than in the group without such therapy: a recent (≤6 months) hospitalization and medical treatment including digoxin or based on >3 different drugs. Neither the value of the CHADS2 score, nor the geriatric characteristics could be correlated with the presence or the absence of an anticoagulation therapy. More research is thus required to identify and clarify the relative importance of patient-, physician-, and health care system-related hurdles for the prescription of oral anticoagulation therapy in older patients with AF.

Identifiers

PMID25295192
PMCPMC4175391
OpenAlexW2056715949

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.