Evidence map›Paper›PMID 25295125›Full record

ArticleCellular and molecular bioengineering2014

Depolarization of Cellular Resting Membrane Potential Promotes Neonatal Cardiomyocyte Proliferation In Vitro.

Jen-Yu Lan, Corin Williams, Michael Levin, Lauren Deems Black

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular bioengineering, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Ion Channels in Gliomas-From Molecular Basis to Treatment.International journal of molecular sciences · 2023
    Review
  3. The multifaceted nature of endogenous cardiac regeneration.Frontiers in cardiovascular medicine · 2023
    Review
  4. Article
  5. Article
  6. Kir4.1 is coexpressed with stemness markers in activated astrocytes in the injured brain and a Kir4.1 inhibitor BaClThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
    Article
  7. Review
  8. Article
  9. Article
  10. L-type voltage-gated CaProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  11. Hyperosmolar Potassium (KCartilage · 2019
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Biofield Physiology: A Framework for an Emerging Discipline.Global advances in health and medicine · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jen-Yu LanDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155 USA.
Corin WilliamsDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155 USA.
Michael LevinDepartment of Biology, Tufts University, Medford, MA 02155 USA ; Center for Regenerative and Developmental Biology, Tufts University, Medford, MA 02155 USA.
Lauren Deems BlackDepartment of Biomedical Engineering, Tufts University, Medford, MA 02155 USA ; Cellular, Molecular and Developmental Biology Program, Sackler Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111 USA.
Tufts University · US

Funding

Restoring LV Function Post-MI Using Fibrin-Gel Based Engineered MyocardiumR00HL093358 · NHLBI · TUFTS UNIVERSITY MEDFORD · PI BLACK III, LAUREN D. · 2010 to 2012
$747k
The role of the extracellular biophysical and biomechanical milieu in CHDsR21HL115570 · NHLBI · TUFTS UNIVERSITY MEDFORD · PI BLACK III, LAUREN D. · 2012 to 2013
$380k
Towards repairing congenital heart defects: The effects of fetal cardiac extracelF32HL112538 · NHLBI · TUFTS UNIVERSITY MEDFORD · PI WILLIAMS, CORIN · 2012 to 2013
$101k
NHLBI NIH HHS F32 HL112538NHLBI NIH HHS R00 HL093358NHLBI NIH HHS R21 HL115570
6 · The paper itself

Abstract

Cardiomyocytes (CMs) undergo a rapid transition from hyperplastic to hypertrophic growth soon after birth, which is a major challenge to the development of engineered cardiac tissue for pediatric patients. Resting membrane potential (V

Indexed as

Akt pathwayCardiac FibroblastsCell cycleouabainpotassium gluconate

Identifiers

PMID25295125
PMCPMC4185190
OpenAlexW2098236325

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.