Evidence map›Paper›PMID 25294779›Full record

SynthesisJournal of hazardous materials2015

Epistemology of contaminants of emerging concern and literature meta-analysis.

Rolf U Halden

Open access · greenAbstract readMeta-Analysis
In one paragraph

Synthesis in Journal of hazardous materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
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  4. BioinspiredACS omega · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Rolf U HaldenCenter for Environmental Security, The Biodesign Institute, Security and Defense Systems Initiative, Arizona State University, 781 E. Terrace Mall, Tempe, AZ 85287, USA; Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA. Electronic address: halden@asu.edu.
Johns Hopkins University · US

Funding

In Situ Sampling Tool for Assessing Bioavailability and Toxicity of SedimentsR01ES020889 · NIEHS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI DENSLOW, NANCY D, HALDEN, ROLF U · 2011 to 2013
$874k
NIEHS NIH HHS 1R01ES020889NIEHS NIH HHS R01 ES020889
6 · The paper itself

Abstract

A meta-analysis was conducted to inform the epistemology, or theory of knowledge, of contaminants of emerging concern (CECs). The CEC terminology acknowledges the existence of harmful environmental agents whose identities, occurrences, hazards, and effects are not sufficiently understood. Here, data on publishing activity were analyzed for 12 CECs, revealing a common pattern of emergence, suitable for identifying past years of peak concern and forecasting future ones: dichlorodiphenyltrichloroethane (DDT; 1972, 2008), trichloroacetic acid (TCAA; 1972, 2009), nitrosodimethylamine (1984), methyl tert-butyl ether (2001), trichloroethylene (2005), perchlorate (2006), 1,4-dioxane (2009), prions (2009), triclocarban (2010), triclosan (2012), nanomaterials (by 2016), and microplastics (2022 ± 4). CECs were found to emerge from obscurity to the height of concern in 14.1 ± 3.6 years, and subside to a new baseline level of concern in 14.5 ± 4.5 years. CECs can emerge more than once (e.g., TCAA, DDT) and the multifactorial process of emergence may be driven by inception of novel scientific methods (e.g., ion chromatography, mass spectrometry and nanometrology), scientific paradigm shifts (discovery of infectious proteins), and the development, marketing and mass consumption of novel products (antimicrobial personal care products, microplastics and nanomaterials). Publishing activity and U.S. regulatory actions were correlated for several CECs investigated.

Indexed as

CarbanilidesDDTDimethylnitrosamineDioxanesEnvironmental MonitoringEnvironmental PollutantsGovernment RegulationMethyl EthersNanostructuresPerchloratesPolymersPrionsTrichloroacetic AcidTrichloroethyleneTriclosanUnited States1,4-dioxaneCarbanilidesDDTDimethylnitrosamineDioxanesEnvironmental PollutantsMethyl Ethersmethyl tert-butyl etherperchloratePerchloratesPolymersPrionsTrichloroacetic AcidTrichloroethylenetriclocarbanTriclosanMicroplasticsNanomaterialsNDMAPrionsTrichloroethyleneTriclosan

Identifiers

PMID25294779
PMCPMC4253867
OpenAlexW2027632791

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.