ArticleThe American journal of tropical medicine and hygiene2014
Seroprevalence of neutralizing antibodies against dengue virus in two localities in the state of Morelos, Mexico.
Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04947111 (Serological Study of Dengue and Characterization of Immune Response in Ten Endemic and Non-Endemic Cities in Mexico), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Serological Study of Dengue and Characterization of Immune Response in Ten Endemic and Non-Endemic Cities in Mexico
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Socioeconomic risk markers of arthropod-borne virus (arbovirus) infections: a systematic literature review and meta-analysis.BMJ global health · 2022Pooled it
- Overall and serotype-specific dengue virus transmission intensity in Mexico, 2016-2023: A modelling study of case-notification data.PLoS medicine · 2026Article
- Epidemiological Characteristics of Dengue Disease in Mexico (2014-2025): A Descriptive Analysis of a Hyperendemic Country.Pathogens (Basel, Switzerland) · 2026Review
- Microclimate factors related to dengue virus burden clusters in two endemic towns of Mexico.PloS one · 2024Article
- Convergent trends and spatiotemporal patterns of Aedes-borne arboviruses in Mexico and Central America.PLoS neglected tropical diseases · 2023Article
- Hyperendemic Dengue and Possible Zika Circulation in the Westernmost Region of the Indonesian Archipelago.Viruses · 2022Article
- Use of seroprevalence to guide dengue vaccination plans for older adults in a dengue non-endemic country.PLoS neglected tropical diseases · 2021Article
- Co-infection of Dengue, Zika and Chikungunya in a group of pregnant women from Tuxtla Gutiérrez, Chiapas: Preliminary data. 2019.PLoS neglected tropical diseases · 2020Article
- Risk of dengue virus infection according to serostatus in individuals from dengue endemic areas of Mexico.Scientific reports · 2020Article
- Dengue Underestimation in Guangzhou, China: Evidence of Seroprevalence in Communities With No Reported Cases Before a Large Outbreak in 2014.Open forum infectious diseases · 2019Article
- Arbovirus circulation among febrile patients at the greater Accra Regional Hospital, Ghana.BMC research notes · 2019Article
- Opportunities for improved surveillance and control of dengue from age-specific case data.eLife · 2019Article
- Seroprevalence for dengue virus in a hyperendemic area and associated socioeconomic and demographic factors using a cross-sectional design and a geostatistical approach, state of São Paulo, Brazil.BMC infectious diseases · 2019Article
- Differential human antibody repertoires following Zika infection and the implications for serodiagnostics and disease outcome.Nature communications · 2019Article
- Dengue seroprevalence in a cohort of schoolchildren and their siblings in Yucatan, Mexico (2015-2016).PLoS neglected tropical diseases · 2018Article
- Seroepidemiology of Dengue, Zika, and Yellow Fever Viruses among Children in the Democratic Republic of the Congo.The American journal of tropical medicine and hygiene · 2018Article
- Stratified sero-prevalence revealed overall high disease burden of dengue but suboptimal immunity in younger age groups in Pune, India.PLoS neglected tropical diseases · 2018Article
- Current challenges and implications for dengue, chikungunya and Zika seroprevalence studies worldwide: A scoping review.PLoS neglected tropical diseases · 2018Article
- Molecular and Clinical Characterization of Chikungunya Virus Infections in Southeast Mexico.Viruses · 2018Article
- Seroprevalence of dengue in school children in Mexico ages 6-17 years, 2016.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Humoral immune response against dengue virus (DENV) is an important component in dengue-endemic transmission. We conducted a cross-sectional nested cohort study to determine the seroprevalence and frequency of neutralizing antibodies against DENV serotypes in two endemic localities in the state of Morelos, Mexico. The cohort participants (N = 1,196) were screened to determine previous exposure to DENV. Overall seroprevalence was 76.6% (95% confidence interval [95% CI] = 73.6-79.2), and prevalence of neutralizing antibodies in the 5- to 9-year-old group was 82.5% (95% CI = 67.2-92.7), 45% (95% CI = 29.3-61.5), and 65% (95% CI = 48.3-79.4) for DENV-1, DENV-2, and DENV-3, respectively. For participants older than 10 years, the observed seroprevalence was above 60% for each serotype, except DENV-4 in the 10- to 25-year-old group (42.9%); 81% of humoral responses were multitypic. The outcomes of our study contribute to understanding the immune component of dengue transmission and provide focal information for the evaluation of vaccine candidates under development.
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