ReviewSeminars in cardiothoracic and vascular anesthesia2015
Circadian rhythms in anesthesia and critical care medicine: potential importance of circadian disruptions.
Review in Seminars in cardiothoracic and vascular anesthesia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Daylight on Period 2 Protein and Glycolytic Enzymes in Human Buccal Mucosa and Blood Samples
Effects of Procedure Started in the Morning and Afternoon on Early Postoperative Sleep Function and Postoperative Recovery in Patients Under General Anesthesia
Who cites it
30 citing papers in PubMed, 57 citations in OpenAlex.
- The Impact of Morning Surgery or Afternoon Surgery on Postoperative Sleep Quality and Melatonin Levels of Elderly Patients: A Prospective, Randomized Study.Nature and science of sleep · 2022Trial
- Influence of Intravenous Norepinephrine Administration on Melatonin Plasma Concentration in Awake and Anaesthetised Healthy Adult Volunteers.Journal of pineal research · 2026Article
- Light therapy in medicine: where do we stand?Annals of translational medicine · 2026Review
- RHO GTPase by L1 GABAergic neurons in frontal cortex and L6 glutamatergic neurons in prefrontal cortex differentiates states of unconsciousness.Scientific reports · 2025Article
- Effects of LED Versus Fluorescent Task Lighting on Sleep Quality and Daytime Function in Windowless Office Environments.International journal of environmental research and public health · 2025Article
- How does circadian rhythm affect postoperative pain after pediatric acute appendicitis surgery?Anesthesia and pain medicine · 2024Article
- Circadian Influences on Myocardial Ischemia-Reperfusion Injury and Heart Failure.Circulation research · 2024Review
- Enhancing circadian rhythms-the circadian MEGA bundle as novel approach to treat critical illness.Annals of translational medicine · 2023Review
- Daytime Variation of Chloral Hydrate-Associated Sedation Outcomes: A Propensity-Matched Cohort Study.Journal of clinical medicine · 2023Article
- The relationship between anesthesia and melatonin: a review.Frontiers in pharmacology · 2023Review
- Impact of the period of the day on all-cause mortality and major cardiovascular complications after arterial vascular surgeries.PloS one · 2023Article
- Effects of multiple exposures to general anesthesia on the sleep quality of children after plastic surgery in Beijing, China: a cohort study.Sleep and biological rhythms · 2022Article
- Multi-tissue transcriptional changes and core circadian clock disruption following intensive care.Frontiers in physiology · 2022Article
- Association of natural light exposure and delirium according to the presence or absence of windows in the intensive care unit.Acute and critical care · 2021Article
- Article
- Targeting circadian PER2 as therapy in myocardial ischemia and reperfusion injury.Chronobiology international · 2021Review
- Intense Light Pretreatment Improves Hemodynamics, Barrier Function and Inflammation in a Murine Model of Hemorrhagic Shock Lung.Military medicine · 2020Article
- Intense light as anticoagulant therapy in humans.PloS one · 2020Article
- Circadian disruption of core body temperature in trauma patients: a single-center retrospective observational study.Journal of intensive care · 2020Article
- Circadian-Hypoxia Link and its Potential for Treatment of Cardiovascular Disease.Current pharmaceutical design · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
The rotation of the earth and associated alternating cycles of light and dark--the basis of our circadian rhythms--are fundamental to human biology and culture. However, it was not until 1971 that researchers first began to describe the molecular mechanisms for the circadian system. During the past few years, groundbreaking research has revealed a multitude of circadian genes affecting a variety of clinical diseases, including diabetes, obesity, sepsis, cardiac ischemia, and sudden cardiac death. Anesthesiologists, in the operating room and intensive care units, manage these diseases on a daily basis as they significantly affect patient outcomes. Intriguingly, sedatives, anesthetics, and the intensive care unit environment have all been shown to disrupt the circadian system in patients. In the current review, we will discuss how newly acquired knowledge of circadian rhythms could lead to changes in clinical practice and new therapeutic concepts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.