Evidence map›Paper›PMID 25294497›Full record

ReviewGlycoconjugate journal2014

Glycosyltransferases, glycosylation and atherosclerosis.

Qianghong Pu, Chao Yu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Glycoconjugate journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
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  9. Review
  10. Review
  11. Mechanisms of Regulation of the Chemokine-Receptor Network.International journal of molecular sciences · 2017
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Qianghong PuInstitute of Life Science, Chongqing Medical University, Box 174#, No. 1 Yixueyuan Road, Yuzhong District, Chongqing, 400016, People's Republic of China.
Chao Yu
Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases arising from atherosclerosis are currently the leading cause of mortality worldwide. Leukocyte recruitment is a key step for the successful initiation of atherosclerosis and occurs predominantly in the inflamed endothelium. Leukocyte recruitment is mediated by a group of adhesive molecules and chemokine receptors, which are often glycosylated protein. Recent studies demonstrated that post-translational glycosylation by glycosyltransferases is necessary for adhesive molecules and chemokine receptors activities. Several glycosyltransferases, such as α2,3-sialyltransferases IV, α1,3-fucosyltransferases IV and VII, core 2 β1,6-N-acetylglucosaminyltransferase-I, are considered to participate in the synthesis of glycosylation for adhesive molecules and chemokine receptors, and the initiation of atherosclerotic lesions. In this review, we will discuss new data concerning the roles of different glycosyltransferases in atherogenesis. The knowledge of glycosyltransferases in atherogenesis offers the opportunity to develop novel therapeutic strategies.

Indexed as

Protein Processing, Post-TranslationalAtherosclerosisBlood VesselsCell Adhesion MoleculesCell MovementEndothelium, VascularGlycosylationGlycosyltransferasesHumansLeukocytesPolysaccharidesReceptors, ChemokineSignal TransductionCell Adhesion MoleculesGlycosyltransferasesPolysaccharidesReceptors, Chemokine

Identifiers

PMID25294497
OpenAlexW2077824317

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.