ArticleMedical science monitor : international medical journal of experimental and clinical research2014
Relationship of clinical and microbiological variables in patients with type 1 diabetes mellitus and periodontitis.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Oral microbiome alterations in individuals with type 1 diabetes: a systematic review.Clinical oral investigations · 2026Pooled it
- Host insulin resistance caused byFrontiers in cellular and infection microbiology · 2023Pooled it
- Review
- The rise and evolving role ofCurrent research in microbial sciences · 2025Review
- Alterations in subgingival microbiome and advanced glycation end-products levels in periodontitis with and without type 1 diabetes mellitus: a cross-sectional study.BMC oral health · 2024Article
- Investigating the Interplay: Periodontal Disease and Type 1 Diabetes Mellitus-A Comprehensive Review of Clinical Studies.International journal of molecular sciences · 2024Review
- Pangenomic Study of Fusobacterium nucleatum Reveals the Distribution of Pathogenic Genes and Functional Clusters at the Subspecies and Strain Levels.Microbiology spectrum · 2023Article
- Differences in intestinal microbiota profiling after upper and lower gastrointestinal surgery.Journal of the Chinese Medical Association : JCMA · 2021Article
- Microbial characteristics across different tongue coating types in a healthy population.Journal of oral microbiology · 2021Article
- The Interrelationship Between Diabetes, IL-17 and Bone Loss.Current osteoporosis reports · 2020Review
- Oral microbiota-induced periodontitis: a new risk factor of metabolic diseases.Reviews in endocrine & metabolic disorders · 2019Review
- The Oral Microbiota Is Modified by Systemic Diseases.Journal of dental research · 2019Review
- The long term microbiota and metabolic status in patients with colorectal cancer after curative colon surgery.PloS one · 2019Article
- What is the influence of tonsillectomy on the level of periodontal pathogens on the tongue dorsum and in periodontal pockets.BMC oral health · 2018Article
- Interleukin-17A Gene Variability in Patients with Type 1 Diabetes Mellitus and Chronic Periodontitis: Its Correlation with IL-17 Levels and the Occurrence of Periodontopathic Bacteria.Mediators of inflammation · 2016Article
- Alterations of the Subgingival Microbiota in Pediatric Crohn's Disease Studied Longitudinally in Discovery and Validation Cohorts.Inflammatory bowel diseases · 2015Article
- Microbiological, lipid and immunological profiles in children with gingivitis and type 1 diabetes mellitus.Journal of applied oral science : revista FOBArticle
- Influence of glycemic control on the levels of subgingival periodontal pathogens in patients with generalized chronic periodontitis and type 2 diabetes.Journal of applied oral science : revista FOBArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of the study was to analyze how metabolic control of type 1 diabetes is related to clinical and microbiological periodontal parameters. MATERIAL AND
methodsThe study involved 56 subjects aged from 19 to 50 years divided into 2 groups: healthy subjects (the H group), and diabetic (type 1 diabetes) patients with chronic untreated generalized periodontitis (the DM group). The glycosylated hemoglobin value (HbA1c) was determined using the UniCel DxC 800 SYNCHRON System (Beckman Coulter, USA), and the concentration in blood was measured by the turbidimetric immunoinhibition method. A molecular genetic assay (Micro-IDent plus, Germany) was used to detect periodontopathogenic bacteria in plaque samples. Periodontitis was confirmed by clinical and radiological examination.
resultsFusobacterium nucleatum, Capnocytophaga species, and Eikenella corrodens were the most frequently found bacteria in dental plaque samples (77.8%, 66.7%, and 33.4%, respectively), whereas Aggregatibacter actinomycetemcomitans was identified 40.7% less frequently in the DM group than in the H group. The strongest relationship was observed between the presence of 2 periodontal pathogens - F. nucleatum and Capnocytophaga spp. - and poorer metabolic control in type 1 diabetes patients (HbA1c) and all clinical parameters of periodontal pathology.
conclusionsPeriodontal disease was more evident in type 1 diabetic patients, and the prevalence of periodontitis was greatly increased in subjects with poorer metabolic control.
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Registered trials
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