ReviewEndocrine2015
Prediabetes and associated disorders.
Review in Endocrine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 3 syntheses or guidelines pooled it, 159 citations in OpenAlex.
- Association Between Prediabetes and Erectile Dysfunction: A Meta-Analysis.Frontiers in endocrinology · 2021Pooled it
- Association between prediabetes and risk of cardiovascular disease and all cause mortality: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2016Pooled it
- Risk of Coronary Heart Disease in Different Criterion of Impaired Fasting Glucose: A Meta-Analysis.Medicine · 2015Pooled it
- Peptide hormones and risk for future cardiovascular events among prediabetics: a 20-year follow-up in the OPERA study.Annals of medicineTrial
- Surface-based cortical thickness and gyrification mapping with data-driven prediction of cognitive impairment in prediabetes.IBRO neuroscience reports · 2026Article
- Quantitative metabolomics and machine learning identify differential metabolomic biomarkers across normoglycaemia, pre-diabetes and diabetes in a Qinghai Plateau population.BMJ public health · 2026Article
- Identification of pre-diabetes subphenotypes for type 2 diabetes, related vascular complications and mortality.BMJ open diabetes research & care · 2025Article
- Physiological processes induced by different types of physical activity that either oppose or enhance postprandial glucose tolerance.Frontiers in endocrinology · 2025Review
- Incidence of depression in patients with cardiovascular disease and type 2 diabetes: a nationwide cohort study.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- Peripheral insulin resistance attenuates cerebral glucose metabolism and impairs working memory in healthy adults.npj metabolic health and disease · 2024Article
- Sex differences in the association between metabolic score for insulin resistance and the reversion to normoglycemia in adults with prediabetes: a cohort study.Diabetology & metabolic syndrome · 2024Article
- The association of regional cerebral blood flow and glucose metabolism in normative ageing and insulin resistance.Scientific reports · 2024Article
- The association between triglyceride-glucose index and related parameters and risk of cardiovascular disease in American adults under different glucose metabolic states.Diabetology & metabolic syndrome · 2024Article
- Pregestational Prediabetes Induces Maternal Hypothalamic-Pituitary-Adrenal (HPA) Axis Dysregulation and Results in Adverse Foetal Outcomes.International journal of molecular sciences · 2024Article
- Clinical and Metabolic Characterization of Women With Gestational Diabetes Mellitus Within the First Year Postpartum.Journal of the Endocrine Society · 2024Article
- Construction of a 3-year risk prediction model for developing diabetes in patients with pre-diabetes.Frontiers in endocrinology · 2024Article
- Article
- Assessing interstitial fluid dynamics in type 2 diabetes mellitus and prediabetes cases through diffusion tensor imaging analysis along the perivascular space.Frontiers in aging neuroscience · 2024Article
- Prevalence and correlates of pre-diabetes in Sub-Saharan Africa using Demographic and Health Survey Data: a cross-sectional study.BMJ open · 2023Article
- Microvascular and Endothelial Dysfunction in Prediabetes.Life (Basel, Switzerland) · 2023Review
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prediabetes represents an elevation of plasma glucose above the normal range but below that of clinical diabetes. Prediabetes includes individuals with IFG, IGT, IFG with IGT and elevated HbA1c levels. Insulin resistance and β-cell dysfunction are characteristic of this disorder. The diagnosis of prediabetesis is vital as both IFG and IGT are indeed well-known risk factors for type 2 diabetes with a greater risk in the presence of combined IFG and IGT. Furthermore, as will be illustrated in this review, prediabetes is associated with associated disorders typically only considered in with established diabetes. These include cardiovascular disease, periodontal disease, cognitive dysfunction, microvascular disease, blood pressure abnormalities, obstructive sleep apnea, low testosterone, metabolic syndrome, various biomarkers, fatty liver disease, and cancer. As the vast majority of individuals with prediabetes are unaware of their diagnosis, it is therefore vital that the associated conditions are identified, particularly in the presence of mild hyperglycemia, so they may benefit from early intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.