Evidence map›Paper›PMID 25293698›Full record

ArticleEnvironmental health and preventive medicine2015

Biomonitoring of mercury, cadmium, and lead exposure in Japanese children: a cross-sectional study.

Cimi Ilmiawati, Takahiko Yoshida, Toshihiro Itoh, Yoshihiko Nakagi, Yasuaki Saijo, Yoshihiko Sugioka, Mineshi Sakamoto, Akihiko Ikegami, Masanori Ogawa, Fujio Kayama

Open access · goldAbstract read
In one paragraph

Article in Environmental health and preventive medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. What do we know about exposure of Iranians to cadmium? Findings from a systematic review.Environmental science and pollution research international · 2018
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  14. Element Levels and Predictors of Exposure in the Hair of Ethiopian Children.International journal of environmental research and public health · 2020
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  15. Blood Mercury Levels in Children with Kawasaki Disease and Disease Outcome.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Cimi IlmiawatiDepartment of Environmental and Preventive Medicine, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Takahiko Yoshida
Toshihiro Itoh
Yoshihiko Nakagi
Yasuaki Saijo
Yoshihiko Sugioka
Mineshi Sakamoto
Akihiko Ikegami
Masanori Ogawa
Fujio Kayama
Asahikawa Medical University · JPJichi Medical University · JPAndalas University · IDNational Institute for Minamata Disease · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo measure current Hg, Cd, and Pb exposure in Japanese children, and to estimate dietary intakes of foods responsible for high body burden.

methodsBlood, hair, and urine samples were collected from 9 to 10-year-old 229 children in Asahikawa and measured for Hg, Cd, and Pb in these matrices. Diet history questionnaire was used to estimate intake of marine foods and other food items. Hg level was measured by cold vapor atomic absorption spectrometry. Cd and Pb levels were determined with inductively coupled plasma mass spectrometry.

resultsGeometric mean (GM) of blood Hg, Cd, and Pb was 4.55 μg/L, 0.34 μg/L, and 0.96 μg/dL, respectively. Urinary Cd level was 0.34 μg/g creatinine (GM) and hair Hg was 1.31 μg/g (GM). Approximately one-third (35%) of blood samples had Hg level above the U.S. EPA reference dose (RfD; 5.8 μg/L). Hair Hg level exceeded U.S. EPA RfD (1.2 μg/g) in 59 % samples. Children in the upper quartile of blood Hg level had significantly higher intake of large predatory fish species compared to those in the lower quartile of blood Hg.

conclusionsThose with high blood Hg level may be explained by more frequent intake of big predatory fish. Cd and Pb exposure is generally low among Japanese children. As no safety margin exists for Pb exposure and high exposure to MeHg is noted in Japanese population; periodic biomonitoring and potential health risk assessment should continue in high-risk populations, notably among children.

Indexed as

SeafoodBiomarkersCadmiumChildCross-Sectional StudiesDietEnvironmental ExposureEnvironmental MonitoringEnvironmental PollutantsFemaleFood ContaminationHairHumansJapanLeadMaleBiomarkersCadmiumEnvironmental PollutantsLeadMercuryMetals, Heavy

Identifiers

PMID25293698
PMCPMC4284244
OpenAlexW2102720303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.