ArticleThe journal of sexual medicine2015
Changes in erectile dysfunction over time in relation to Framingham cardiovascular risk in the Boston Area Community Health (BACH) Survey.
Article in The journal of sexual medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 38 citations in OpenAlex.
- Erectile Dysfunction: A Comprehensive Review of Pathophysiology, Diagnosis and Contemporary Management.Medicina (Kaunas, Lithuania) · 2026Review
- Erectile dysfunction, type 2 diabetes, and cardiovascular disease: a narrative review and insights from a global real-world cohort analysis.Frontiers in clinical diabetes and healthcare · 2026Review
- The association between serum 25-hydroxyvitamin D levels and erectile dysfunction: a two-sample Mendelian randomization analysis.International journal of impotence research · 2024Article
- Association of total testosterone levels with cardiometabolic diseases in men with erectile dysfunction.Sexual medicine · 2024Article
- Quantifying the number of US men with erectile dysfunction who are potential candidates for penile prosthesis implantation.Sexual medicine · 2023Article
- Investigating self-reported efficacy of lifestyle medicine approaches to tackle erectile dysfunction: a cross-sectional eSurvey based study.BMC urology · 2023Article
- Plant-based diet index and erectile dysfunction in the Health Professionals Follow-Up Study.BJU international · 2022Article
- Endothelial Dysfunction, Erectile Deficit and Cardiovascular Disease: An Overview of the Pathogenetic Links.Biomedicines · 2022Review
- Association of Diet With Erectile Dysfunction Among Men in the Health Professionals Follow-up Study.JAMA network open · 2020Article
- Misdiagnosis And Undertreatment Of Erectile Dysfunction In The Portuguese Primary Health Care.Sexual medicine · 2019Article
- An Empirical vs Risk-Based Approach Algorithm to Intracavernosal Injection Therapy: A Prospective Study.Sexual medicine · 2017Article
- Health and lifestyle factors associated with sexual difficulties in men - results from a study of Australian men aged 18 to 55 years.BMC public health · 2016Article
- Sexuality in Nigerian older adults.The Pan African medical journal · 2015Article
- Association of sociodemographic factors with various domains of alcohol-induced sexual dysfunction - An Indian perspective.Industrial psychiatry journalArticle
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
introductionErectile dysfunction (ED) is associated with cardiovascular disease (CVD); however, the association between change in ED status over time and future underlying CVD risk is unclear.
aimThe aim of this study was to investigate the association between change in ED status and Framingham CVD risk, as well change in Framingham risk.
methodsWe studied 965 men free of CVD in the Boston Area Community Health (BACH) Survey, a longitudinal cohort study with three assessments. ED was assessed with the five-item International Index of Erectile Function at BACH I (2002-2005) and BACH II (2007-2010) and classified as no ED/transient ED/persistent ED. CVD risk was assessed with 10-year Framingham CVD risk algorithm at BACH I and BACH III (2010-2012). Linear regression models controlled for baseline age, socio-demographic and lifestyle factors, as well as baseline Framingham risk. Models were also stratified by age (≥/< 50 years).
main outcome measuresFramingham CVD risk and change in Framingham CVD risk were the main outcome measures.
resultsTransient and persistent ED was significantly associated with increased Framingham risk and change in risk over time in univariate and age-adjusted models. In younger men, persistent ED was associated with a Framingham risk that was 1.58 percentage points higher (95% confidence interval [CI]: 0.11, 3.06) and in older men, a Framingham risk that was 2.54 percentage points higher (95% CI: -1.5, 6.59), compared with those without ED. Change in Framingham risk over time was also associated with transient and persistent ED in men <50 years, but not in older men.
conclusionsData suggest that even after taking into account other CVD risk factors, transient and persistent ED is associated with Framingham CVD risk and a greater increase in Framingham risk over time, particularly in younger men. Findings further support clinical assessment of CVD risk in men presenting with ED, especially those under 50 years.
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