ArticlePhysiological reports2014
Mechanisms underlying the postexercise baroreceptor-mediated suppression of heat loss.
Article in Physiological reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- The Effect of Dietary Supplements on Endurance Exercise Performance and Core Temperature in Hot Environments: A Meta-analysis and Meta-regression.Sports medicine (Auckland, N.Z.) · 2021Pooled it
- Exploring the mechanisms underpinning sweating: the development of a specialized ventilated capsule for use with intradermal microdialysis.Physiological reports · 2016Trial
- Fluid replacement modulates oxidative stress- but not nitric oxide-mediated cutaneous vasodilation and sweating during prolonged exercise in the heat.American journal of physiology. Regulatory, integrative and comparative physiology · 2017Article
- Wearing graduated compression stockings augments cutaneous vasodilation but not sweating during exercise in the heat.Physiological reports · 2017Article
- Wearing graduated compression stockings augments cutaneous vasodilation in heat-stressed resting humans.European journal of applied physiology · 2017Article
- The mechanisms underlying the muscle metaboreflex modulation of sweating and cutaneous blood flow in passively heated humans.Physiological reports · 2017Article
- The interactive contributions of Na(+) /K(+) -ATPase and nitric oxide synthase to sweating and cutaneous vasodilatation during exercise in the heat.The Journal of physiology · 2016Article
- iNOS-dependent sweating and eNOS-dependent cutaneous vasodilation are evident in younger adults, but are diminished in older adults exercising in the heat.Journal of applied physiology (Bethesda, Md. : 1985) · 2016Article
- Muscle metaboreceptors modulate postexercise sweating, but not cutaneous blood flow, independent of baroreceptor loading status.American journal of physiology. Regulatory, integrative and comparative physiology · 2015Article
- Intradermal administration of ATP augments methacholine-induced cutaneous vasodilation but not sweating in young males and females.American journal of physiology. Regulatory, integrative and comparative physiology · 2015Article
- Local infusion of ascorbate augments NO-dependent cutaneous vasodilatation during intense exercise in the heat.The Journal of physiology · 2015Article
- Do nitric oxide synthase and cyclooxygenase contribute to the heat loss responses in older males exercising in the heat?The Journal of physiology · 2015Article
- Cutaneous vascular and sweating responses to intradermal administration of ATP: a role for nitric oxide synthase and cyclooxygenase?The Journal of physiology · 2015Article
- Body temperature regulation in diabetes.Temperature (Austin, Tex.)Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reports indicate that postexercise heat loss is modulated by baroreceptor input; however, the mechanisms remain unknown. We examined the time-dependent involvement of adenosine receptors, noradrenergic transmitters, and nitric oxide (NO) in modulating baroreceptor-mediated changes in postexercise heat loss. Eight males performed two 15-min cycling bouts (85% VO2max) each followed by a 45-min recovery in the heat (35°C). Lower body positive (LBPP), negative (LBNP), or no (Control) pressure were applied in three separate sessions during the final 30-min of each recovery. Four microdialysis fibres in the forearm skin were perfused with: (1) lactated Ringer's (Ringer's); (2) 4 mmol·L(-1) Theophylline (inhibits adenosine receptors); (3) 10 mmol·L(-1) Bretylium (inhibits noradrenergic transmitter release); or (4) 10 mmol·L(-1) l-NAME (inhibits NO synthase). We measured cutaneous vascular conductance (CVC; percentage of maximum) calculated as perfusion units divided by mean arterial pressure, and local sweat rate. Compared to Control, LBPP did not influence CVC at l-NAME, Theophylline or Bretylium during either recovery (P > 0.07); however, CVC at Ringer's was increased by ~5-8% throughout 30 min of LBPP during Recovery 1 (all P < 0.02). In fact, CVC at Ringer's was similar to Theophylline and Bretylium during LBPP. Conversely, LBNP reduced CVC at all microdialysis sites by ~7-10% in the last 15 min of Recovery 2 (all P < 0.05). Local sweat rate was similar at all treatment sites as a function of pressure condition (P > 0.10). We show that baroreceptor input modulates postexercise CVC to some extent via adenosine receptors, noradrenergic vasoconstriction, and NO whereas no influence was observed for postexercise sweating.
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