Evidence map›Paper›PMID 25291788›Full record

ArticleIEEE transactions on medical imaging2015

Ultrasound shear wave elasticity imaging quantifies coronary perfusion pressure effect on cardiac compliance.

Maryam Vejdani-Jahromi, Matt Nagle, Gregg E Trahey, Patrick D Wolf

Open access · bronzeAbstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Medical Imaging Technology and Imaging Agents.Advances in experimental medicine and biology · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Biomedical physics & engineering express · 2018
    Article
  13. Quantifying Myocardial Contractility Changes Using Ultrasound-Based Shear Wave Elastography.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2017
    Article
  14. A Comparison of Acoustic Radiation Force-Derived Indices of Cardiac Function in the Langendorff Perfused Rabbit Heart.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2016
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maryam Vejdani-Jahromi
Matt Nagle
Gregg E Trahey
Patrick D Wolf
Duke University · US

Funding

Acoustic Radiation Force Impulse (ARFI) Imaging of Cardiac TissueR37HL096023 · NHLBI · DUKE UNIVERSITY · PI TRAHEY, GREGG E. · 2009 to 2018
$5.2M
Clinical Evaluation of an Ultrasound Based Imaging System for Guiding Cardiac AblR01EB012484 · NIBIB · DUKE UNIVERSITY · PI WOLF, PATRICK D · 2010 to 2013
$3.5M
Acoustic Radiation Force Imaging of ArteriesR01HL075485 · NHLBI · DUKE UNIVERSITY · PI TRAHEY, GREGG E. · 2004 to 2012
$3.2M
NHLBI NIH HHS R01 HL075485NHLBI NIH HHS R37HL075485NHLBI NIH HHS R37 HL096023NIBIB NIH HHS R01 EB012484NIBIB NIH HHS R01EB012484
6 · The paper itself

Abstract

Diastolic heart failure (DHF) is a major source of cardiac related morbidity and mortality in the world today. A major contributor to, or indicator of DHF is a change in cardiac compliance. Currently, there is no accepted clinical method to evaluate the compliance of cardiac tissue in diastolic dysfunction. Shear wave elasticity imaging (SWEI) is a novel ultrasound-based elastography technique that provides a measure of tissue stiffness. Coronary perfusion pressure affects cardiac stiffness during diastole; we sought to characterize the relationship between these two parameters using the SWEI technique. In this work, we demonstrate how changes in coronary perfusion pressure are reflected in a local SWEI measurement of stiffness during diastole. Eight Langendorff perfused isolated rabbit hearts were used in this study. Coronary perfusion pressure was changed in a randomized order (0-90 mmHg range) and SWEI measurements were recorded during diastole with each change. Coronary perfusion pressure and the SWEI measurement of stiffness had a positive linear correlation with the 95% confidence interval (CI) for the slope of 0.009-0.011 m/s/mmHg ( R(2) = 0.88 ). Furthermore, shear modulus was linearly correlated to the coronary perfusion pressure with the 95% CI of this slope of 0.035-0.042 kPa/mmHg ( R(2) = 0.83). In conclusion, diastolic SWEI measurements of stiffness can be used to characterize factors affecting cardiac compliance specifically the mechanical interaction (cross-talk) between perfusion pressure in the coronary vasculature and cardiac muscle. This relationship was found to be linear over the range of pressures tested.

Indexed as

AnimalsEchocardiographyElasticity Imaging TechniquesHeartHeart Failure, DiastolicLinear ModelsMyocardial ReperfusionRabbits

Identifiers

PMID25291788
PMCPMC4765376
OpenAlexW2039772897

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.