ArticlePloS one2014
Measuring soluble ICAM-1 in African populations.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Missense Genetic Variation of ICAM1 and Incident Heart Failure.Journal of cardiac failure · 2023Article
- Arterial stiffness is associated with oxidative stress and endothelial activation among persons with treated HIV in Zambia.Southern African journal of HIV medicine · 2021Article
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Authors and funding
4 authors.
Funding
Abstract
The level of plasma soluble ICAM-1 (sICAM-1) has been associated with the pathogenesis of several diseases. Previously, a commercial antibody was reported not to recognize an ICAM-1 allele known as ICAM-1kilifi prevalent among African populations. However, that study was based on 19 samples from African Americans of whom 13 had the wild type allele, five heterozygotes and one homozygote. Here, we compare plasma sICAM-1 measures using three different commercial antibodies in samples from Kenyan children genotyped for ICAM-1kilifi allele. We show that two of these antibodies have some degree of deficiency in detecting the ICAM-1kilifi allele. Consideration of the antibody used to measure sICAM-1 is important as up to 30% of the populations in Africa harbour this allele.
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