Evidence map›Paper›PMID 25289156›Full record

ArticleSurgical neurology international2014

Effects of teriparatide on lung function and pain relief in women with multiple osteoporotic vertebral compression fractures.

Chien-Min Chen, Ping-Yi Lin, Ying-Chieh Chen, Yong Jin, Abel Po-Hao Huang, Sheng-Hao Lin, Ming-Tai Hsing, Yen-Po Cheng, Chun-Yuan Cheng, Chung-Tien Lin

Abstract read
In one paragraph

Article in Surgical neurology international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Chien-Min ChenDivision of Neurosurgery, Department of Surgery, Changhua Christian Hospital, Changhua, Department and Graduate Institute of Veterinary Medicine, Taiwan.
Ping-Yi LinTransplant Medicine and Surgery Research Centre, Changhua Christian Hospital, Changhua, Taiwan.
Ying-Chieh ChenDivision of Neurosurgery, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan.
Yong JinDepartment of Neurosurgery, Affiliated Taizhou Municipal Hospital, Taizhou University, China.
Abel Po-Hao HuangDivision of Neurosurgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Sheng-Hao LinDivision of Chest Medicine, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Institute of Biomedical Science, National Chung-Hsing University, Taichung, Taiwan.
Ming-Tai HsingDivision of Neurosurgery, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan.
Yen-Po ChengDivision of Neurosurgery, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan.
Chun-Yuan ChengDivision of Neurosurgery, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan.
Chung-Tien LinDepartment and Graduate Institute of Veterinary Medicine and Institute of Veterinary Clinical Science, School of Veterinary Medicine, National Taiwan University, Taiwan.
Changhua Christian Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoporosis is predominantly a condition of the elderly. In this study, we evaluated the effects of teriparatide on lung function and pain relief in elderly women with multiple osteoporotic vertebral compression fractures.

methodsA total of 37 patients who received teriparatide treatment during the period January 2010 to December 2011 were enrolled. Dual-energy X-ray absorptiometry scans were used to measure bone mineral density (BMD) and lung function was measured using a MasterScreen Body Jaeger spirometer. Forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) values were recorded. The Oswestry Disability Index (ODI) and the Visual Analog Scale (VAS) for pain were used to evaluate physical health and pain intensity, respectively, at baseline and after 6 months of teriparatide treatment.

resultsMean BMD at the lumbar spine increased from 0.716 g/cm(2) at baseline to 0.829 g/cm(2) after 6 months of treatment. In addition, both mean FVC and FEV1 values after 6 months of treatment were significantly higher than baseline values (99.01% and 100.06% vs. 87.62% and 90.62%, respectively). Teriparatide treatment also resulted in a significant reduction in self-reported pain intensity and a significant improvement in physical health as measured by VAS and ODI scores, respectively.

conclusionsIn addition to increasing BMD, teriparatide treatment improves the lung function and results in diminished pain intensity in women with multiple osteoporotic vertebral compression fractures.

Indexed as

Lung functionosteoporosisteriparatide

Identifiers

PMID25289156
PMCPMC4173302
OpenAlexW2106015854

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.