Trial reportPsychopharmacology2015
Glucose administration and cognitive function: differential effects of age and effort during a dual task paradigm in younger and older adults.
Trial report in Psychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- The Impact of Free and Added Sugars on Cognitive Function: A Systematic Review and Meta-Analysis.Nutrients · 2023Pooled it
- How Does Fasting Affect Cognition? An Updated Systematic Review (2013-2020).Current nutrition reports · 2021Pooled it
- Fuel for Thought? A Systematic Review of Neuroimaging Studies into Glucose Enhancement of Cognitive Performance.Neuropsychology review · 2020Pooled it
- The Relationship Between Dietary Patterns, Cognition, and Cardiometabolic Health in Healthy, Older Adults.Nutrients · 2024Observational
- The impact of food stimuli and fasting on cognitive control in task switching.Psychological research · 2024Article
- The Impact of Free Sugar on Human Health-A Narrative Review.Nutrients · 2023Review
- The Effect of Nighttime Snacking on Cognitive Function in Older Adults: Evidence from Observational and Experimental Studies.Nutrients · 2022Article
- Cognitive glucose sensitivity-proposing a link between cognitive performance and reliance on external glucose uptake.Nutrition & diabetes · 2022Article
- Review
- Aging is not equal across memory systems.Neurobiology of learning and memory · 2020Article
- Cognitive dysfunction during hypoglycemia in an elderly subject without diabetes.Diabetology international · 2020Article
- Amide proton transfer-weighted magnetic resonance imaging of human brain aging at 3 Tesla.Quantitative imaging in medicine and surgery · 2020Article
- Goals in Nutrition Science 2020-2025.Frontiers in nutrition · 2020Review
- Functional Connectivity of the Anterior and Posterior Hippocampus: Differential Effects of Glucose in Younger and Older Adults.Frontiers in aging neuroscience · 2020Article
- The Effects of Carbohydrates, in Isolation and Combined with Caffeine, on Cognitive Performance and Mood-Current Evidence and Future Directions.Nutrients · 2018Review
- Increasing Neuroplasticity to Bolster Chronic Pain Treatment: A Role for Intermittent Fasting and Glucose Administration?The journal of pain · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
rationaleCurrent research suggests that glucose facilitates performance on cognitive tasks which possess an episodic memory component and a relatively high level of cognitive demand. However, the extent to which this glucose facilitation effect is uniform across the lifespan is uncertain.
methodsThis study was a repeated measures, randomised, placebo-controlled, cross-over trial designed to assess the cognitive effects of glucose in younger and older adults under single and dual task conditions. Participants were 24 healthy younger (average age 20.6 years) and 24 healthy older adults (average age 72.5 years). They completed a recognition memory task after consuming drinks containing 25 g glucose and a placebo drink, both in the presence and absence of a secondary tracking task. RESULTS AND
conclusionsGlucose enhanced recognition memory response time and tracking precision during the secondary task, in older adults only. These findings do not support preferential targeting of hippocampal function by glucose, rather they suggest that glucose administration differentially increases the availability of attentional resources in older individuals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.