Observational studyIntensive care medicine2014
Methicillin-resistant Staphylococcus aureus bloodstream infections are associated with a higher energy deficit than other ICU-acquired bacteremia.
Observational study in Intensive care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Association between protein and energy intake during acute phase and sepsis outcomes: a retrospective cohort study.Scientific reports · 2025Article
- Usability study of a new tool for nutritional and glycemic management in adult intensive care: Glucosafe 2.Journal of clinical monitoring and computing · 2021Article
- Utilization of Intensive Care Unit Nutrition Consultation Is Associated With Reduced Mortality.JPEN. Journal of parenteral and enteral nutrition · 2020Article
- Epinephrine Dose Has a Preventive Effect on the Occurrence of Stress Ulcer-Induced Gastrointestinal Bleeding in Critically Ill Patients.Digestive diseases and sciences · 2018Observational
- Can calculation of energy expenditure based on COCritical care (London, England) · 2017Observational
- Focus on optimization of early antimicrobial therapy in ICU-acquired infections.Intensive care medicine · 2016Review
- Staphylococcal Toxic Shock Syndrome Caused by an Intravaginal Product. A Case Report.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2016Article
- Impact of early nutrition and feeding route on outcomes of mechanically ventilated patients with shock: a post hoc marginal structural model study.Intensive care medicine · 2015Article
- Year in review in Intensive Care Medicine 2014: III. Severe infections, septic shock, healthcare-associated infections, highly resistant bacteria, invasive fungal infections, severe viral infections, Ebola virus disease and paediatrics.Intensive care medicine · 2015Review
- Energy deficit is clinically relevant for critically ill patients: yes.Intensive care medicine · 2015Article
- Parenteral nutrition: never say never.Critical care (London, England) · 2015Review
- Nutrition in the ICU: proof of the pudding is in the tasting.Intensive care medicine · 2015Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCaloric insufficiency during the first week of intensive care unit (ICU) stay was reported to be associated with increased infection rates, especially ICU-acquired bloodstream infection (ICU-BSI). However, the predisposition to ICU-BSI by a given pathogen remains not well known. We aimed to determine the impact of early energy-calorie deficit on the pathogens responsible for ICU-BSI.
designProspective, observational, cohort study in a 18-bed medical ICU of a tertiary care hospital.
methodsDaily energy balance (energy-calorie intakes minus calculated energy-calorie expenditure) was compared according to the microbiological results of the blood cultures of 92 consecutive prolonged (at least 96 h) acute mechanically ventilated patients who developed a first episode of ICU-BSI.
resultsAmong the 92 ICU-BSI, nine were due to methicillin-resistant Staphylococcus aureus (MRSA). The cumulated energy deficit of patients with MRSA ICU-BSI was greater than those with ICU-BSI caused by other pathogens (-1,348 ± 260 vs -1,000 ± 401 kcal/day from ICU admission to day of ICU-BSI, p = 0.008). ICU admission, risk factors for nosocomial infections, nutritional status, and conditions potentially limiting feeding did not differ significantly between the two groups. Patients with MRSA ICU-BSI had lower delivered energy and similar energy expenditure, causing higher energy deficits. More severe energy deficit and higher rate of MRSA blood cultures (p = 0.01 comparing quartiles) were observed.
conclusionsEarly in-ICU energy deficit was associated with MRSA ICU-BSI in prolonged acute mechanically ventilated patients. Results suggest that limiting the early energy deficit could be a way to optimize MRSA ICU-BSI prevention.
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